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| Nodo | Tipo | Descripción | Visible | Title | Importance | Lens id | Journal | Date | Node size | Link |
|---|---|---|---|---|---|---|---|---|---|---|
| 111-1.23 | New |
The Impact of COVID-19 on Radiology Trainees Matthew D. Alvin, Elizabeth George, Francis Deng, et al. DOI: 10.1148/radiol.2020201222 |
Visibilidad | The Impact of COVID-19 on Radiology Trainees | 1.23 | 064-522-912-524-932 | Radiology | 2020-03-29 | 12.3 | |
| 11-1.59 | New |
Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. Scott Simpson, Fernando U. Kay, Suhny Abbara, et al. DOI: 10.1148/ryct.2020200152 |
Visibilidad | Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. | 1.59 | 008-414-334-467-980 | Radiology: Cardiothoracic Imaging | 2020-03-28 | 15.9 | |
| 112-1.01 | New |
Potential Effects of Coronaviruses on the Cardiovascular System Mohammad Madjid, Payam Safavi-Naeini, Scott D. Solomon, et al. DOI: 10.1001/jamacardio.2020.1286 |
Visibilidad | Potential Effects of Coronaviruses on the Cardiovascular System | 1.01 | 003-052-408-102-208 | JAMA Cardiology | 2020-03-29 | 10.1 | |
| 113-0.86 | New |
Covid-19: risk factors for severe disease and death Rachel E Jordan, Peymane Adab, K K Cheng DOI: 10.1136/bmj.m1198 |
Visibilidad | Covid-19: risk factors for severe disease and death | 0.86 | 008-537-158-868-338 | BMJ | 2020-03-29 | 8.6 | |
| 114-0.81 | New |
Internet hospitals help prevent and control the epidemic of COVID-19 in China: a multicenter user profiling study (Preprint) Kai Gong, Zhong Xu, Zhefeng Cai, et al. Along with the spread of novel coronavirus disease (COVID-19), internet hospitals in China were engaged in the epidemic prevention and control, offering epidemic-related online services and medical supports to the public. People from all over the world are plagued by the pandemic coronavirus. The virus, which has already spread from China to other world, has already taken away numerous fresh lives. The number of victims is increasing with the shift. People around the world are already taking precautions against the virus. The busiest w...
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Visibilidad | Coronavirus: Symptoms, diagnosis, treatment and prevention (Preprint) | 0.63 | 044-217-872-481-969 | 2020-03-29 | 6.3 | ||
| 117-0.59 | New |
The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19) J. Randall Curtis, Erin K. Kross, Renee D. Stapleton DOI: 10.1001/jama.2020.4894 |
Visibilidad | The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19) | 0.59 | 110-036-168-210-398 | JAMA | 2020-03-29 | 5.9 | |
| 118-0.57 | New |
The Role of Emergency Radiology in COVID-19: From Preparedness to Diagnosis Muhammad Umer Nasir, James Roberts, Nestor L. Muller, et al. DOI: 10.1177/0846537120916419 |
Visibilidad | The Role of Emergency Radiology in COVID-19: From Preparedness to Diagnosis | 0.57 | 024-049-393-090-535 | Canadian Association of Radiologists Journal | 2020-03-29 | 5.7 | |
| 1-1.87 | New |
Frequency and Distribution of Chest Radiographic Findings in COVID-19 Positive Patients Ho Yuen Frank Wong, Hiu Yin Sonia Lam, Ambrose Ho-Tung Fong, et al. DOI: 10.1148/radiol.2020201160 |
Visibilidad | Frequency and Distribution of Chest Radiographic Findings in COVID-19 Positive Patients | 1.87 | 050-425-192-041-584 | Radiology | 2020-03-29 | 18.7 | |
| 119-0.57 | Old |
Molecular diversity of coronaviruses in bats Patrick C. Y. Woo, Susanna K. P. Lau, Kenneth S. M. Li, et al. The existence of coronaviruses in bats is unknown until the recent discovery of bat-SARS-CoV in Chinese horseshoe bats and a novel group 1 coronavirus in other bat species. Among 309 bats of 13 species captured from 20 different locations in rural areas of Hong Kong over a 16-month period, coronaviruses were amplified from anal swabs of 37 (12%) bats by RT-PCR. Phylogenetic analysis of RNA-depende... DOI: 10.1016/j.virol.2006.02.041 |
Visibilidad | Molecular diversity of coronaviruses in bats | 0.57 | 060-501-577-846-679 | Virology | 2018-05-12 | 5.7 | |
| 120-0.49 | New |
Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Tao Chen, Di Wu, Huilong Chen, et al. DOI: 10.1136/bmj.m1091 |
Visibilidad | Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study | 0.49 | 102-092-559-762-655 | BMJ | 2020-03-29 | 4.9 | |
| 121-0.45 | New | Visibilidad | Turbulent Gas Clouds and Respiratory Pathogen Emissions | 0.45 | 053-894-370-041-730 | JAMA | 2020-03-28 | 4.5 | ||
| 122-0.43 | Old |
Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Ali Moh Zaki, Sander van Boheemen, Theo M. Bestebroer, et al. A previously unknown coronavirus was isolated from the sputum of a 60-year-old man who presented with acute pneumonia and subsequent renal failure with a fatal outcome in Saudi Arabia. The virus (called HCoV-EMC) replicated readily in cell culture, producing cytopathic effects of rounding, detachment, and syncytium formation. The virus represents a novel betacoronavirus species. The closest known ... DOI: 10.1056/nejmoa1211721 |
Visibilidad | Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia | 0.43 | 023-671-383-084-282 | The New England Journal of Medicine | 2018-05-11 | 4.3 | |
| 123-0.43 | New |
Peri-operative and critical care concerns in coronavirus pandemic SukhminderJit Singh Bajwa, Rashi Sarna, Chashamjot Bawa, et al. DOI: 10.4103/ija.ija_272_20 |
Visibilidad | Peri-operative and critical care concerns in coronavirus pandemic | 0.43 | 197-959-359-730-996 | Indian Journal of Anaesthesia | 2020-03-30 | 4.3 | |
| 124-0.42 | New | Visibilidad | Using rapid online surveys to assess perceptions during infectious disease outbreaks: a cross-sectional survey on Covid-19 among the general public in the United States and United Kingdom (Preprint) | 0.42 | 145-082-742-767-949 | Journal of Medical Internet Research | 2020-03-29 | 4.2 | ||
| 125-0.4 | New |
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) Riccardo M. Inciardi, Laura Lupi, Gregorio Zaccone, et al. DOI: 10.1001/jamacardio.2020.1096 |
Visibilidad | Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) | 0.4 | 103-879-856-404-796 | JAMA Cardiology | 2020-03-29 | 4.0 | |
| 126-0.39 | Old |
A Novel Coronavirus from Patients with Pneumonia in China, 2019 Na Zhu, Dingyu Zhang, Wenling Wang, et al. Summary In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through... DOI: 10.1056/nejmoa2001017 |
Visibilidad | A Novel Coronavirus from Patients with Pneumonia in China, 2019 | 0.39 | 011-720-951-980-353 | The New England Journal of Medicine | 2020-01-26 | 3.9 | |
| 127-0.39 | New |
On the Frontline of the COVID-19 Outbreak Suzanne Watnick, Elizabeth McNamara DOI: 10.2215/cjn.03540320 |
Visibilidad | On the Frontline of the COVID-19 Outbreak | 0.39 | 045-054-213-099-160 | Clinical Journal of the American Society of Nephrology | 2020-03-30 | 3.9 | |
| 128-0.39 | Old |
Coronaviruses and the human airway: a universal system for virus-host interaction studies Hulda R. Jonsdottir, Ronald Dijkman Human coronaviruses (HCoVs) are large RNA viruses that infect the human respiratory tract. The emergence of both Severe Acute Respiratory Syndrome and Middle East Respiratory syndrome CoVs as well as the yearly circulation of four common CoVs highlights the importance of elucidating the different mechanisms employed by these viruses to evade the host immune response, determine their tropism and id... DOI: 10.1186/s12985-016-0479-5 |
Visibilidad | Coronaviruses and the human airway: a universal system for virus-host interaction studies | 0.39 | 043-145-118-781-736 | Virology Journal | 2018-05-12 | 3.9 | |
| 129-0.37 | New | Visibilidad | Suggestions on Improving the Hand Hygiene for the Prevention and Control Personnel during the Novel Coronavirus (COVID-19) Epidemic Outbreak | 0.37 | 164-056-902-545-385 | Service Science and Management | 2020-03-28 | 3.7 | ||
| 130-0.34 | Old |
Host-directed therapies for improving poor treatment outcomes associated with the middle east respiratory syndrome coronavirus infections Alimuddin Zumla, Esam I. Azhar, Yaseen M. Arabi, et al. Summary Three years after its first discovery in Jeddah Saudi Arabia, the novel zoonotic pathogen of humans, the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) continues to be a major threat to global health security. 1 Sporadic community acquired cases of MERS continue to be reported from the Middle East. The recent nosocomial outbreaks in hospitals in Seoul, Korea and at the National Gu... DOI: 10.1016/j.ijid.2015.09.005 |
Visibilidad | Host-directed therapies for improving poor treatment outcomes associated with the middle east respiratory syndrome coronavirus infections | 0.34 | 012-127-185-744-309 | International Journal of Infectious Diseases | 2018-05-12 | 3.4 | |
| 131-0.33 | Old |
Identification of Severe Acute Respiratory Syndrome in Canada Susan M. Poutanen, Donald E. Low, Bonnie Henry, et al. background Severe acute respiratory syndrome (SARS) is a condition of unknown cause that has recently been recognized in patients in Asia, North America, and Europe. This report summarizes the initial epidemiologic findings, clinical description, and diagnostic findings that followed the identification of SARS in Canada. methods SARS was first identified in Canada in early March 2003. We collected... DOI: 10.1056/nejmoa030634 |
Visibilidad | Identification of Severe Acute Respiratory Syndrome in Canada | 0.33 | 048-318-297-371-12X | The New England Journal of Medicine | 2018-05-12 | 3.3 | |
| 132-0.33 | Old |
A novel coronavirus associated with severe acute respiratory syndrome. Thomas G. Ksiazek, Dean D. Erdman, Cynthia S. Goldsmith, et al. background A worldwide outbreak of severe acute respiratory syndrome (SARS) has been associated with exposures originating from a single ill health care worker from Guangdong Province, China. We conducted studies to identify the etiologic agent of this outbreak. methods We received clinical specimens from patients in six countries and tested them, using virus isolation techniques, electron-microsc... DOI: 10.1056/nejmoa030781 |
Visibilidad | A novel coronavirus associated with severe acute respiratory syndrome. | 0.33 | 043-391-337-502-219 | The New England Journal of Medicine | 2018-05-12 | 3.3 | |
| 133-0.31 | Old |
Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission Benoit Guery, Julien Poissy, Loubna El Mansouf, et al. Summary Background Human infection with a novel coronavirus named Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia and the Middle East in September, 2012, with 44 laboratory-confirmed cases as of May 23, 2013. We report detailed clinical and virological data for two related cases of MERS-CoV disease, after nosocomial transmission of the virus from one pa... DOI: 10.1016/s0140-6736(13)60982-4 |
Visibilidad | Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission | 0.31 | 031-810-638-617-640 | The Lancet | 2018-05-12 | 3.1 | |
| 134-0.29 | New |
The effect of human mobility and control measures on the COVID-19 epidemic in China Moritz U. G. Kraemer, Chia-Hung Yang, Bernardo Gutierrez, et al. DOI: 10.1126/science.abb4218 |
Visibilidad | The effect of human mobility and control measures on the COVID-19 epidemic in China | 0.29 | 031-883-225-563-477 | Science | 2020-03-28 | 2.9 | |
| 135-0.28 | New | Visibilidad | Psychiatric Aspects of Coronavirus (2019-nCoV) Infection | 0.28 | 077-798-648-024-232 | Iranian Journal of Psychiatry and Behavioral Sciences | 2020-03-27 | 2.8 | ||
| 136-0.28 | Old |
Middle East respiratory syndrome coronavirus: Implications for health care facilities Helena C. Maltezou, Sotirios Tsiodras Background Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel coronavirus that causes a severe respiratory disease with high case fatality rate. Starting in March 2014, a dramatic increase of cases has occurred in the Arabian Peninsula, many of which were acquired in health care settings. As of May 9, 2014, 536 laboratory-confirmed cases and 145 deaths have been reported globally. ... DOI: 10.1016/j.ajic.2014.06.019 |
Visibilidad | Middle East respiratory syndrome coronavirus: Implications for health care facilities | 0.28 | 073-523-847-978-786 | American Journal of Infection Control | 2018-05-12 | 2.8 | |
| 137-0.27 | New |
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Jasper F. W. Chan, Shuofeng Yuan, Kin-Hang Kok, et al. Summary Background An ongoing outbreak of pneumonia associated with a novel coronavirus was reported in Wuhan city, Hubei province, China. Affected patients were geographically linked with a local wet market as a potential source. No data on person-to-person or nosocomial transmission have been published to date. Methods In this study, we report the epidemiological, clinical, laboratory, radiologi... DOI: 10.1016/s0140-6736(20)30154-9 |
Visibilidad | A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster | 0.27 | 006-185-699-645-541 | The Lancet | 2020-01-26 | 2.7 | |
| 138-0.27 | New |
Covid-19: a remote assessment in primary care Trisha Greenhalgh, Gerald Choon Huat Koh, Josip Car DOI: 10.1136/bmj.m1182 |
Visibilidad | Covid-19: a remote assessment in primary care | 0.27 | 022-980-392-295-105 | BMJ | 2020-03-29 | 2.7 | |
| 139-0.27 | Old |
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Dawei Wang, Bo Hu, Chang Hu, et al. Importance In December 2019, novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patients is limited. Objective To describe the epidemiological and clinical characteristics of NCIP. Design, Setting, and Participants Retrospective, single-center case series of the 138 ... DOI: 10.1001/jama.2020.1585 |
Visibilidad | Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China | 0.27 | 038-116-875-675-064 | JAMA | 2020-02-09 | 2.7 | |
| 140-0.26 | Old |
Full-genome Deep Sequencing and Phylogenetic Analysis of Novel Human Betacoronavirus Matthew Cotten, Tommy T-Y Lam, Simon J. Watson, et al. A novel betacoronavirus associated with lethal respiratory and renal complications was recently identified in patients from several countries in the Middle East. We report the deep genome sequencing of the virus directly from a patient’s sputum sample. Our high-throughput sequencing yielded a substantial depth of genome sequence assembly and showed the minority viral variants in the specimen. Deta... DOI: 10.3201/eid1905.130057 |
Visibilidad | Full-genome Deep Sequencing and Phylogenetic Analysis of Novel Human Betacoronavirus | 0.26 | 030-206-317-283-136 | Emerging Infectious Diseases | 2018-05-12 | 2.6 | |
| 141-0.25 | New | Visibilidad | Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors | 0.25 | 119-389-021-199-092 | Immunotherapy | 2020-03-28 | 2.5 | ||
| 142-0.24 | Old |
Identification of a novel coronavirus in patients with severe acute respiratory syndrome Christian Drosten, Stephan Günther, Wolfgang Preiser, et al. BACKGROUND: The severe acute respiratory syndrome (SARS) has recently been identified as a new clinical entity. SARS is thought to be caused by an unknown infectious agent. METHODS: Clinical specimens from patients with SARS were searched for unknown viruses with the use of cell cultures and molecular techniques. RESULTS: A novel coronavirus was identified in patients with SARS. The virus was isol... DOI: 10.1056/nejmoa030747 |
Visibilidad | Identification of a novel coronavirus in patients with severe acute respiratory syndrome | 0.24 | 012-113-809-211-723 | The New England Journal of Medicine | 2018-05-12 | 2.4 | |
| 143-0.24 | Old |
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir Hamzah A. Mohd, Jaffar A. Al-Tawfiq, Ziad A. Memish Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance and phylogenetic studies suggest a bat origin. The disease is heavily endemic in dromedary camel populations of East Africa and the Middle East. It is unclear as to when the virus was introduce... DOI: 10.1186/s12985-016-0544-0 |
Visibilidad | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir | 0.24 | 104-650-355-294-892 | Virology Journal | 2018-05-12 | 2.4 | |
| 144-0.23 | Old |
The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China - International Journal of Infectious Diseases David S.C. Hui The city of Wuhan in China is the focus of global attention due to an outbreak of a febrile respiratory illness due to a coronavirus 2019-nCoV. In December 2019, there was an outbreak of pneumonia of unknown cause in Wuhan, Hubei province in China, with an epidemiological link to the Huanan Seafood Wholesale Market where there was also sale of live animals. Notification of the WHO on 31 Dec 2019 b... DOI: 10.1016/j.ijid.2020.01.009 |
Visibilidad | The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China - International Journal of Infectious Diseases | 0.23 | 032-500-896-849-586 | International Journal of Infectious Diseases | 2020-01-23 | 2.3 | |
| 145-0.23 | New |
Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using age-adjusted data from the outbreak on the Diamond Princess cruise ship, February 2020 Timothy W Russell, Joel Hellewell, Christopher I Jarvis, et al. DOI: 10.2807/1560-7917.es.2020.25.12.2000256 |
Visibilidad | Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using age-adjusted data from the outbreak on the Diamond Princess cruise ship, February 2020 | 0.23 | 035-870-337-056-034 | Eurosurveillance | 2020-03-28 | 2.3 | |
| 146-0.23 | New |
Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future Swaminathan Sethu, Rohit Shetty, Arkasubhra Ghosh, et al. DOI: 10.4103/ijo.ijo_639_20 |
Visibilidad | Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future | 0.23 | 049-542-157-415-525 | Indian Journal of Ophthalmology | 2020-03-29 | 2.3 | |
| 147-0.23 | Old |
Taking forward a ‘One Health’ approach for turning the tide against the Middle East respiratory syndrome coronavirus and other zoonotic pathogens with epidemic potential Alimuddin Zumla, Osman Dar, Richard Kock, et al. Summary The appearance of novel pathogens of humans with epidemic potential and high mortality rates have threatened global health security for centuries. Over the past few decades new zoonotic infectious diseases of humans caused by pathogens arising from animal reservoirs have included West Nile virus, Yellow fever virus, Ebola virus, Nipah virus, Lassa Fever virus, Hanta virus, Dengue fever vir... DOI: 10.1016/j.ijid.2016.06.012 |
Visibilidad | Taking forward a ‘One Health’ approach for turning the tide against the Middle East respiratory syndrome coronavirus and other zoonotic pathogens with epidemic potential | 0.23 | 016-819-513-559-042 | International Journal of Infectious Diseases | 2018-05-12 | 2.3 | |
| 148-0.23 | Old |
The Role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis Ruth McBride, Burtram C. Fielding A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The subsequent efficient human-to-human transmission of this virus eventually affected more than 30 countries worldwide, resulting in a mortality rate of ~10% of infected individuals. The spread of the virus was ultimately controlled by... DOI: 10.3390/v4112902 |
Visibilidad | The Role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis | 0.23 | 034-122-131-728-499 | Viruses | 2018-05-11 | 2.3 | |
| 149-0.22 | New |
Frequent Convulsive Seizures in an Adult Patient with COVID-19: A Case Report Narges Karimi, Athena Sharifi Razavi, Nima Rouhani DOI: 10.5812/ircmj.102828 |
Visibilidad | Frequent Convulsive Seizures in an Adult Patient with COVID-19: A Case Report | 0.22 | 069-448-515-726-978 | Iranian Red Crescent Medical Journal | 2020-03-29 | 2.2 | |
| 150-0.22 | Old |
Community case clusters of Middle East respiratory syndrome coronavirus in Hafr Al-Batin, Kingdom of Saudi Arabia: a descriptive genomic study. Ziad A. Memish, Matthew Cotten, Simon J. Watson, et al. The Middle East respiratory syndrome coronavirus (MERS-CoV) was first described in September 2012 and to date 86 deaths from a total of 206 cases of MERS-CoV infection have been reported to the WHO. Camels have been implicated as the reservoir of MERS-CoV, but the exact source and mode of transmission for most patients remain unknown. During a 3 month period, June to August 2013, there were 12 pos... DOI: 10.1016/j.ijid.2014.03.1372 |
Visibilidad | Community case clusters of Middle East respiratory syndrome coronavirus in Hafr Al-Batin, Kingdom of Saudi Arabia: a descriptive genomic study. | 0.22 | 011-683-474-227-00X | International Journal of Infectious Diseases | 2018-05-12 | 2.2 | |
| 151-0.22 | Old |
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia Qun Li, Xuhua Guan, Peng Wu, et al. Abstract Background The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the... DOI: 10.1056/nejmoa2001316 |
Visibilidad | Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia | 0.22 | 001-281-857-268-277 | The New England Journal of Medicine | 2020-02-06 | 2.2 | |
| 152-0.21 | Old |
In silico analysis of ORF1ab in coronavirus HKU1 genome reveals a unique putative cleavage site of coronavirus HKU1 3C-like protease. Patrick C. Y. Woo, Yi Huang, Susanna K. P. Lau, et al. Recently we have described the discovery and complete genome sequence of a novel coronavirus associated with pneumonia, coronavirus HKU1 (CoV-HKU1). In this study, a detailed in silico analysis of the ORF1ab, encoding the 7,182-amino acid replicase polyprotein in the CoV-HKU1 genome showed that the replicase polyprotein of CoV-HKU1 is cleaved by its papain-like proteases and 3C-like protease (3CLp... DOI: 10.1111/j.1348-0421.2005.tb03681.x |
Visibilidad | In silico analysis of ORF1ab in coronavirus HKU1 genome reveals a unique putative cleavage site of coronavirus HKU1 3C-like protease. | 0.21 | 086-197-944-927-287 | Microbiology and Immunology | 2018-05-12 | 2.1 | |
| 153-0.21 | Old |
Clinical and Molecular Epidemiological Features of Coronavirus HKU1–Associated Community-Acquired Pneumonia Patrick C. Y. Woo, Susanna K. P. Lau, Hoi-Wah Tsoi, et al. Background. Recently, we described the discovery of a novel group 2 coronavirus, coronavirus HKU1 (CoV-HKU1), from a patient with pneumonia. However, the clinical and molecular epidemiological features of CoV-HKU1-associated pneumonia are unknown. Methods. Prospectively collected (during a 12-month period) nasopharyngeal aspirates (NPAs) from patients with community-acquired pneumonia from 4 hospi... DOI: 10.1086/497151 |
Visibilidad | Clinical and Molecular Epidemiological Features of Coronavirus HKU1–Associated Community-Acquired Pneumonia | 0.21 | 070-225-002-077-981 | The Journal of Infectious Diseases | 2018-05-12 | 2.1 | |
| 154-0.2 | Old |
A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case Ali S. Omrani, Mohammad Abdul Matin, Qais A. Haddad, et al. Abstract Background Ninety confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been reported to the World Health Organization. We report the details of a second family cluster of MERS-CoV infections from Riyadh, Saudi Arabia. Methods We present the clinical, laboratory and epidemiological details of 3 patients from a family cluster of MERS-CoV infections. Results The fi... DOI: 10.1016/j.ijid.2013.07.001 |
Visibilidad | A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case | 0.2 | 000-377-446-268-635 | International Journal of Infectious Diseases | 2018-05-12 | 2.0 | |
| 155-0.2 | Old |
Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs K. Anand, John Ziebuhr, Parvesh Wadhwani, et al. A novel coronavirus has been identified as the causative agent of severe acute respiratory syndrome (SARS). The viral main proteinase (Mpro, also called 3CLpro), which controls the activities of the coronavirus replication complex, is an attractive target for therapy. We determined crystal structures for human coronavirus (strain 229E) Mpro and for an inhibitor complex of porcine coronavirus [tran... DOI: 10.1126/science.1085658 |
Visibilidad | Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs | 0.2 | 031-137-736-769-173 | Science | 2018-05-12 | 2.0 | |
| 156-0.19 | Old |
Current advancements and potential strategies in the development of MERS-CoV vaccines Naru Zhang, Shibo Jiang, Lanying Du Middle East respiratory syndrome (MERS) is a newly emerging infectious disease caused by a novel coronavirus, MERS-coronavirus (MERS-CoV), a new member in the lineage C of β-coronavirus (β-CoV). The increased human cases and high mortality rate of MERS-CoV infection make it essential to develop safe and effective vaccines. In this review, the current advancements and potential strategies in the de... DOI: 10.1586/14760584.2014.912134 |
Visibilidad | Current advancements and potential strategies in the development of MERS-CoV vaccines | 0.19 | 047-448-941-251-436 | Expert Review of Vaccines | 2018-05-12 | 1.9 | |
| 157-0.19 | Old |
Mechanisms and enzymes involved in SARS coronavirus genome expression. Volker Thiel, Konstantin A. Ivanov, Ákos Putics, et al. A novel coronavirus is the causative agent of the current epidemic of severe acute respiratory syndrome (SARS). Coronaviruses are exceptionally large RNA viruses and employ complex regulatory mechanisms to express their genomes. Here, we determined the sequence of SARS coronavirus (SARS-CoV), isolate Frankfurt 1, and characterized key RNA elements and protein functions involved in viral genome exp... DOI: 10.1099/vir.0.19424-0 |
Visibilidad | Mechanisms and enzymes involved in SARS coronavirus genome expression. | 0.19 | 012-664-929-949-758 | Journal of General Virology | 2018-05-12 | 1.9 | |
| 158-0.18 | Old |
Understanding the accessory viral proteins unique to the severe acute respiratory syndrome (SARS) coronavirus Yee-Joo Tan, Seng Gee Lim, Wanjin Hong Abstract A novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), infected humans in Guangdong, China, in November 2002 and the subsequent efficient human-to-human transmissions of this virus caused profound disturbances in over 30 countries worldwide in 2003. Eventually, this epidemic was controlled by isolation and there has been no human infection reported since... DOI: 10.1016/j.antiviral.2006.05.010 |
Visibilidad | Understanding the accessory viral proteins unique to the severe acute respiratory syndrome (SARS) coronavirus | 0.18 | 087-754-719-894-648 | Antiviral Research | 2018-05-12 | 1.8 | |
| 159-0.17 | New |
COVID-19 and smoking: A systematic review of the evidence. Constantine I Vardavas, Katerina Nikitara |
Visibilidad | COVID-19 and smoking: A systematic review of the evidence. | 0.17 | 113-907-636-569-175 | Tobacco induced diseases | 2020-03-27 | 1.7 | |
| 160-0.17 | New |
Chest X-ray findings in asymptomatic and minimally symptomatic quarantined patients in Codogno, Italy Michele Bandirali, Luca Maria Sconfienza, Roberta Serra, et al. DOI: 10.1148/radiol.2020201102 |
Visibilidad | Chest X-ray findings in asymptomatic and minimally symptomatic quarantined patients in Codogno, Italy | 0.17 | 114-194-945-757-638 | Radiology | 2020-03-29 | 1.7 | |
| 161-0.16 | New | Visibilidad | Clinical Characteristics of Covid-19 in China | 0.16 | 174-158-304-694-997 | New England Journal of Medicine | 2020-03-29 | 1.6 | ||
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Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome. Susanna K. P. Lau, Patrick C. Y. Woo, Kenneth S. M. Li, et al. Abstract Apart from bat-SARS-CoV, we have identified a novel group 1 coronavirus, bat-CoV HKU2, in Rhinolophus sinicus (Chinese horseshoe bats). Since it has been suggested that the receptor-binding motif (RBM) of SARS-CoV may have been acquired from a group 1 coronavirus, we conducted a surveillance study and identified bat-SARS-CoV and bat-CoV HKU2 in 8.7% and 7.5% respectively of R. sinicus in ... DOI: 10.1016/j.virol.2007.06.009 |
Visibilidad | Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome. | 0.16 | 088-249-963-555-751 | Virology | 2018-05-12 | 1.6 | |
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Recovery from severe novel coronavirus infection Ali Albarrak, Gwen Stephens, Roger Hewson, et al. We describe the third confirmed case of novel coronavirus infection in a resident of the Arabian Peninsula. Our patient presented, as did 2 prior cases, with severe pneumonia and renal dysfunction requiring intensive care support including assisted ventilation. However, unlike the earlier cases, and despite underlying chronic disease and a single kidney, he survived his infection and has been disc... |
Visibilidad | Recovery from severe novel coronavirus infection | 0.16 | 019-540-628-564-176 | Saudi Medical Journal | 2018-05-12 | 1.6 | |
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Contact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012. Udo Buchholz, Marcel A. Müller, Andreas Nitsche, et al. Article published in Eurosurveillance, Volume 18, Issue 8, 21 February 2013. Also available at http://www.eurosurveillance.org |
Visibilidad | Contact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012. | 0.16 | 103-923-519-887-788 | Eurosurveillance | 2018-05-12 | 1.6 | |
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Potential short-term outcome of an uncontrolled COVID-19 epidemic in Lombardy, Italy, February to March 2020 Giorgio Guzzetta, Piero Poletti, Marco Ajelli, et al. DOI: 10.2807/1560-7917.es.2020.25.12.2000293 |
Visibilidad | Potential short-term outcome of an uncontrolled COVID-19 epidemic in Lombardy, Italy, February to March 2020 | 0.14 | 199-898-752-576-960 | Eurosurveillance | 2020-03-28 | 1.4 | |
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Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China Lingkong Zeng, Shiwen Xia, Wenhao Yuan, et al. DOI: 10.1001/jamapediatrics.2020.0878 |
Visibilidad | Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China | 0.14 | 029-952-042-336-436 | JAMA Pediatrics | 2020-03-28 | 1.4 | |
| 167-0.14 | New | Visibilidad | Epidemiology of Covid-19 | 0.14 | 035-699-637-023-712 | New England Journal of Medicine | 2020-03-29 | 1.4 | ||
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Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS Jan Felix Drexler, Victor Max Corman, Christian Drosten Abstract In 2002/2003, a novel coronavirus (CoV) caused a pandemic, infecting more than 8000 people, of whom nearly 10% died. This virus, termed severe acute respiratory syndrome- CoV was linked to a zoonotic origin from rhinolophid bats in 2005. Since then, numerous studies have described novel bat CoVs, including close relatives of the newly emerging Middle East respiratory syndrome (MERS)-CoV. ... DOI: 10.1016/j.antiviral.2013.10.013 |
Visibilidad | Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS | 0.14 | 013-724-959-787-188 | Antiviral Research | 2018-05-12 | 1.4 | |
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Nanshan Chen, Min Zhou, Xuan Dong, et al. In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia. In this retrospective, single-centre study, we included all confirmed cases of 2019-nCoV in Wuhan Jinyintan Hospital from Jan 1 to Jan 20, 2020. Cases were confirmed by real-time RT-PCR an... DOI: 10.1016/s0140-6736(20)30211-7 |
Visibilidad | Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study | 0.14 | 050-494-230-798-801 | The Lancet | 2020-02-06 | 1.4 | |
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Identification of a Novel Coronavirus in Bats Leo L. M. Poon, D. K. W. Chu, Kwan-Hon Chan, et al. Exotic wildlife can act as reservoirs of diseases that are endemic in the area or can be the source of new emerging diseases through interspecies transmission. The recent emergence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) highlights the importance of virus surveillance in wild animals. Here, we report the identification of a novel bat coronavirus through surveillance ... DOI: 10.1128/jvi.79.4.2001-2009.2005 |
Visibilidad | Identification of a Novel Coronavirus in Bats | 0.14 | 037-351-401-792-721 | Journal of Virology | 2018-05-12 | 1.4 | |
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COVID-19 outbreak in Algeria: A mathematical Model to predict cumulative cases Mohamed Hamidouche DOI: 10.2471/blt.20.256065 |
Visibilidad | COVID-19 outbreak in Algeria: A mathematical Model to predict cumulative cases | 0.13 | 038-585-379-036-046 | 2020-03-28 | 1.3 | ||
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Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Chenguang Shen, Zhaoqin Wang, Fang Zhao, et al. DOI: 10.1001/jama.2020.4783 |
Visibilidad | Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma | 0.13 | 182-257-306-271-027 | JAMA | 2020-03-29 | 1.3 | |
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Absence of MERS-CoV antibodies in feral camels in Australia: Implications for the pathogen's origin and spread Gary Crameri, Peter A. Durr, Jennifer A. Barr, et al. Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infections continue to be a serious emerging disease problem internationally with well over 1000 cases and a major outbreak outside of the Middle East region. While the hypothesis that dromedary camels are the likely major source of MERS-CoV infection in humans is gaining acceptance, conjecture continues over the original natural res... DOI: 10.1016/j.onehlt.2015.10.003 |
Visibilidad | Absence of MERS-CoV antibodies in feral camels in Australia: Implications for the pathogen's origin and spread | 0.13 | 002-274-982-281-009 | One Health | 2018-05-12 | 1.3 | |
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Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility Simon Cauchemez, Christophe Fraser, Maria D. Van Kerkhove, et al. Summary Background The novel Middle East respiratory syndrome coronavirus (MERS-CoV) had, as of Aug 8, 2013, caused 111 virologically confirmed or probable human cases of infection worldwide. We analysed epidemiological and genetic data to assess the extent of human infection, the performance of case detection, and the transmission potential of MERS-CoV with and without control measures. Methods W... DOI: 10.1016/s1473-3099(13)70304-9 |
Visibilidad | Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility | 0.13 | 003-797-670-323-555 | Lancet Infectious Diseases | 2018-05-12 | 1.3 | |
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Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Abdullah M. Assiri, Jaffar A. Al-Tawfiq, Abdullah A Al-Rabeeah, et al. Summary Background Middle East respiratory syndrome (MERS) is a new human disease caused by a novel coronavirus (CoV). Clinical data on MERS-CoV infections are scarce. We report epidemiological, demographic, clinical, and laboratory characteristics of 47 cases of MERS-CoV infections, identify knowledge gaps, and define research priorities. Methods We abstracted and analysed epidemiological, demogr... DOI: 10.1016/s1473-3099(13)70204-4 |
Visibilidad | Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study | 0.13 | 028-018-589-005-21X | Lancet Infectious Diseases | 2018-05-12 | 1.3 | |
| 176-0.12 | New | Visibilidad | Analysis on 54 Mortality Cases of Coronavirus Disease 2019 in the Republic of Korea from January 19 to March 10, 2020 | 0.12 | 024-176-041-454-683 | Journal of Korean Medical Science | 2020-03-28 | 1.2 | ||
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Strategies for the prevention and management of coronavirus disease 2019 Wei-jie Guan, Rong-chang Chen, Nan-shan Zhong DOI: 10.1183/13993003.00597-2020 |
Visibilidad | Strategies for the prevention and management of coronavirus disease 2019 | 0.12 | 121-054-149-851-622 | European Respiratory Journal | 2020-03-29 | 1.2 | |
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Italian doctors call for protecting healthcare workers and boosting community surveillance during covid-19 outbreak Filippo Anelli, Giovanni Leoni, Roberto Monaco, et al. DOI: 10.1136/bmj.m1254 |
Visibilidad | Italian doctors call for protecting healthcare workers and boosting community surveillance during covid-19 outbreak | 0.12 | 161-392-196-916-882 | BMJ | 2020-03-29 | 1.2 | |
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Middle East respiratory syndrome (MERS): a new zoonotic viral pneumonia. Cheston B. Cunha, Steven M. Opal Coronaviruses have traditionally been associated with mild upper respiratory tract infections throughout the world. In the fall of 2002, a new coronavirus emerged in in Asia causing severe viral pneumonia, i.e., severe acute respiratory syndrome (SARS). Nearly a decade following the SARS epidemic, a new coronavirus causing severe viral pneumonia has emerged, i.e., middle east respiratory syndrome ... DOI: 10.4161/viru.32077 |
Visibilidad | Middle East respiratory syndrome (MERS): a new zoonotic viral pneumonia. | 0.12 | 055-310-747-165-727 | Virulence | 2018-05-12 | 1.2 | |
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Mosaic Evolution of the Severe Acute Respiratory Syndrome Coronavirus John Stavrinides, David S. Guttman Severe acute respiratory syndrome (SARS) is a deadly form of pneumonia caused by a novel coronavirus, a viral family responsible for mild respiratory tract infections in a wide variety of animals including humans, pigs, cows, mice, cats, and birds. Analyses to date have been unable to identify the precise origin of the SARS coronavirus. We used Bayesian, neighbor-joining, and split decomposition p... DOI: 10.1128/jvi.78.1.76-82.2004 |
Visibilidad | Mosaic Evolution of the Severe Acute Respiratory Syndrome Coronavirus | 0.12 | 033-821-264-813-837 | Journal of Virology | 2018-05-12 | 1.2 | |
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Characterization of a Novel Coronavirus Associated With Severe Acute Respiratory Syndrome Paul A. Rota, M. Steven Oberste, Stephan S. Monroe, et al. In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is simil... DOI: 10.1126/science.1085952 |
Visibilidad | Characterization of a Novel Coronavirus Associated With Severe Acute Respiratory Syndrome | 0.12 | 004-653-726-716-301 | Science | 2018-05-12 | 1.2 | |
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WHO must prioritise the needs of older people in its response to the covid-19 pandemic Peter G Lloyd-Sherlock, Alexandre Kalache, Martin McKee, et al. DOI: 10.1136/bmj.m1164 |
Visibilidad | WHO must prioritise the needs of older people in its response to the covid-19 pandemic | 0.11 | 067-162-525-721-517 | BMJ | 2020-03-27 | 1.1 | |
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Emergence of a Novel Coronavirus (COVID-19): A Protocol for Extending Surveillance Used by the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) and Public Health England (PHE) (Preprint) Simon de Lusignan, Jamie Lopez Bernal, Maria Zambon, et al. DOI: 10.2196/18606 |
Visibilidad | Emergence of a Novel Coronavirus (COVID-19): A Protocol for Extending Surveillance Used by the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) and Public Health England (PHE) (Preprint) | 0.11 | 037-130-567-714-070 | JMIR Public Health and Surveillance | 2020-03-28 | 1.1 | |
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Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage site Andrew D. Davidson, Maia Kavanagh Williamson, Sebastian Lewis, et al. DOI: 10.1101/2020.03.22.002204 |
Visibilidad | Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage site | 0.11 | 013-614-433-735-212 | 2020-03-29 | 1.1 | ||
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Management of Critically Ill Adults With COVID-19 Jason T. Poston, Bhakti K. Patel, Andrew M. Davis DOI: 10.1001/jama.2020.4914 |
Visibilidad | Management of Critically Ill Adults With COVID-19 | 0.11 | 150-748-426-093-89X | JAMA | 2020-03-29 | 1.1 | |
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Geriatric Care during Public Health Emergencies: Lessons Learned from Novel Corona Virus Disease (COVID-19) Pandemic Hoimonty Mazumder, Md Mahbub Hossain, Anupom Das DOI: 10.1080/01634372.2020.1746723 |
Visibilidad | Geriatric Care during Public Health Emergencies: Lessons Learned from Novel Corona Virus Disease (COVID-19) Pandemic | 0.11 | 158-101-102-297-590 | Journal of Gerontological Social Work | 2020-03-29 | 1.1 | |
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Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines Lanying Du, Yuxian He, Yijia Wang, et al. Development of an effective vaccine for severe acute respiratory syndrome (SARS) remains to be a priority to prevent possible re-emergence of SARS coronavirus (SARS-CoV). We previously demonstrated that the receptor-binding domain (RBD) of SARS-CoV S protein is a major target of neutralizing antibodies. This suggests that the RBD may serve as an ideal vaccine candidate. Recombinant adeno-associate... DOI: 10.1016/j.virol.2006.03.049 |
Visibilidad | Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines | 0.11 | 068-904-310-444-512 | Virology | 2018-05-12 | 1.1 | |
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Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia Patrick C. Y. Woo, Susanna Kar-Pui Lau, Yi Huang, et al. Phylogenetic trees constructed using predicted amino acid sequences of putative proteins of coronavirus HKU1 (CoV-HKU1) revealed that CoV-HKU1 formed a distinct branch among group 2 coronaviruses. Of the 14 trees from p65 to nsp10, nine showed that CoV-HKU1 was clustered with murine hepatitis virus. From nsp11, the topologies of the trees changed dramatically. For the eight trees from nsp11 to N, ... DOI: 10.1007/s00705-005-0573-2 |
Visibilidad | Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia | 0.11 | 000-162-542-213-353 | Archives of Virology | 2018-05-12 | 1.1 | |
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Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome Yi Guan, Jsm Peiris, Bo-Jian Zheng, et al. Summary Background Severe acute respiratory syndrome (SARS) is a newly emerged disease caused by a novel coronavirus (SARS-CoV), which spread globally in early 2003, affecting over 30 countries. We have used molecular epidemiology to define the patterns of spread of the virus in Hong Kong and beyond. Methods The case definition of SARS was based on that recommended by WHO. We genetically sequenced... DOI: 10.1016/s0140-6736(03)15259-2 |
Visibilidad | Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome | 0.11 | 064-336-202-963-755 | The Lancet | 2018-05-12 | 1.1 | |
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Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia. Mustafa M. Saad, Ali S. Omrani, Kamran Baig, et al. Summary Objectives To report the experience with Middle East respiratory syndrome coronavirus (MERS-CoV) infection at a single center in Saudi Arabia. Methods Cases of laboratory-confirmed MERS-CoV occurring from October 1, 2012 to May 31, 2014 were reviewed retrospectively. Information sources included medical files, infection control outbreak investigations, and the preventive medicine database ... DOI: 10.1016/j.ijid.2014.09.003 |
Visibilidad | Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia. | 0.11 | 003-861-973-483-349 | International Journal of Infectious Diseases | 2018-05-12 | 1.1 | |
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Molecular biology of severe acute respiratory syndrome coronavirus John Ziebuhr The worldwide epidemic of severe acute respiratory syndrome (SARS) in 2003 was caused by a novel coronavirus called SARS-CoV. Coronaviruses and their closest relatives possess extremely large plus-strand RNA genomes and employ unique mechanisms and enzymes in RNA synthesis that separate them from all other RNA viruses. The SARS epidemic prompted a variety of studies on multiple aspects of the coro... DOI: 10.1016/j.mib.2004.06.007 |
Visibilidad | Molecular biology of severe acute respiratory syndrome coronavirus | 0.1 | 115-731-550-889-684 | Current Opinion in Microbiology | 2018-05-12 | 1.0 | |
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Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. B Hijawi, Mohammad Mousa Al Abdallat, Sayaydeh A, et al. 1Primary Health Care Administration; 2Directorate of Communicable Diseases; 3Laboratory Directorate, Ministry of Health, Jordan (Correspondence to S. Alqasrawi: [email protected]). ABSTRACT In April 2012, an outbreak of acute respiratory illness occurred in a public hospital in Zarqa city, in Jordan; 8 health care workers were among the 11 people affected, 1 of who later died. The cause of ... |
Visibilidad | Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. | 0.1 | 067-803-964-836-006 | Eastern Mediterranean Health Journal | 2018-05-15 | 1.0 | |
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Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia Patrick C. Y. Woo, Susanna K. P. Lau, Chung-Ming Chu, et al. Despite extensive laboratory investigations in patients with respiratory tract infections, no microbiological cause can be identified in a significant proportion of patients. In the past 3 years, several novel respiratory viruses, including human metapneumovirus, severe acute respiratory syndrome (SARS) coronavirus (SARSCoV), and human coronavirus NL63, were discovered. Here we report the discover... DOI: 10.1128/jvi.79.2.884-895.2005 |
Visibilidad | Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia | 0.1 | 086-963-615-655-137 | Journal of Virology | 2018-05-12 | 1.0 | |
| 194-0.09 | New | Visibilidad | COVID-19 R0: Magic number or conundrum? | 0.09 | 049-284-019-979-390 | Infectious disease reports | 2020-03-27 | 0.9 | ||
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Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China Shaobo Shi, Mu Qin, Bo Shen, et al. DOI: 10.1001/jamacardio.2020.0950 |
Visibilidad | Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China | 0.09 | 040-330-478-010-922 | JAMA Cardiology | 2020-03-28 | 0.9 | |
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A survey of 434 clinical trials about coronavirus disease 2019 in China Zikuan Leng, Dongfei Yin, Zhe Zhao, et al. DOI: 10.1002/jmv.25779 |
Visibilidad | A survey of 434 clinical trials about coronavirus disease 2019 in China | 0.09 | 197-125-098-573-257 | Journal of Medical Virology | 2020-03-29 | 0.9 | |
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Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome Vincent C. C. Cheng, Ivan F. N. Hung, B. S. F. Tang, et al. The role of severe acute respiratory syndrome (SARS) coronavirus as an enteric pathogen was investigated in a cohort of 142 patients with SARS who were treated with a standard treatment protocol. Data from daily hematological, biochemical, radiological, and microbiological investigations were prospectively collected, and the correlation of these findings with diarrhea was retrospectively analyzed.... DOI: 10.1086/382681 |
Visibilidad | Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome | 0.09 | 117-596-493-408-808 | Clinical Infectious Diseases | 2018-05-12 | 0.9 | |
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Mass Spectrometric Characterization of Proteins from the SARS Virus A Preliminary Report Oleg V. Krokhin, Yan Li, Anton Andonov, et al. A new coronavirus has been implicated as the causative agent of severe acute respiratory syndrome (SARS). We have used convalescent sera from several SARS patients to detect proteins in the culture supernatants from cells exposed to lavage another SARS patient. The most prominent protein in the supernatant was identified by matrix-assisted laser desorption/ionization time-of-flight mass spectromet... DOI: 10.1074/mcp.m300048-mcp200 |
Visibilidad | Mass Spectrometric Characterization of Proteins from the SARS Virus A Preliminary Report | 0.09 | 072-528-239-689-661 | Molecular & Cellular Proteomics | 2018-05-12 | 0.9 | |
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Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus Matthew Cotten, Simon J. Watson, Alimuddin Zumla, et al. ABSTRACT The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality. In this study, we have determined the MERS-CoV evolutionary rate, documented genetic variants of the virus and their distribution throughout the Arabian peninsula, and identified the genome position... DOI: 10.1128/mbio.01062-13 |
Visibilidad | Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus | 0.09 | 109-155-880-448-590 | Mbio | 2018-05-12 | 0.9 | |
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Severe acute respiratory syndrome coronavirus phylogeny: toward consensus. Alexander E. Gorbalenya, Eric J. Snijder, Willy J. M. Spaan Since the identification of a new coronavirus (severe acute respiratory syndrome coronavirus [SARS-CoV]) as the causative agent of the SARS epidemic in the winter of 2002-2003, the origin of the novel agent has remained a hotly debated topic. Which virus was the immediate ancestor of SARS-CoV, and what are the relationships between SARS-CoV and other previously described coronaviruses? Correct ans... DOI: 10.1128/jvi.78.15.7863-7866.2004 |
Visibilidad | Severe acute respiratory syndrome coronavirus phylogeny: toward consensus. | 0.09 | 034-783-351-316-486 | Journal of Virology | 2018-05-12 | 0.9 | |
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Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China Yi Guan, Bo-Jian Zheng, Y. Q. He, et al. A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-... DOI: 10.1126/science.1087139 |
Visibilidad | Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China | 0.09 | 069-725-146-720-425 | Science | 2018-05-12 | 0.9 | |
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Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection Yijun Ruan, Chia-Lin Wei, Ai Ee Ling, et al. Summary Background The cause of severe acute respiratory syndrome (SARS) has been identified as a new coronavirus. Whole genome sequence analysis of various isolates might provide an indication of potential strain differences of this new virus. Moreover, mutation analysis will help to develop effective vaccines. Methods We sequenced the entire SARS viral genome of cultured isolates from the index ... DOI: 10.1016/s0140-6736(03)13414-9 |
Visibilidad | Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection | 0.09 | 026-777-159-941-985 | The Lancet | 2018-05-12 | 0.9 | |
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Clinical observation and management of COVID-19 patients Taisheng Li, Hongzhou Lu, Wenhong Zhang DOI: 10.1080/22221751.2020.1741327 |
Visibilidad | Clinical observation and management of COVID-19 patients | 0.08 | 037-453-395-523-572 | Emerging Microbes & Infections | 2020-03-28 | 0.8 | |
| 24-0.08 | New | Visibilidad | Coronavirus and Environmental Engineering Science | 0.08 | 022-761-136-878-766 | Environmental Engineering Science | 2020-03-28 | 0.8 | ||
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Coronavirus disease 2019 (COVID-19) outbreak: Could pigs be vectors for human infections? Tanja Opriessnig, Yao-Wei Huang DOI: 10.1111/xen.12591 |
Visibilidad | Coronavirus disease 2019 (COVID-19) outbreak: Could pigs be vectors for human infections? | 0.08 | 164-359-023-966-675 | Xenotransplantation | 2020-03-29 | 0.8 | |
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the emergence of the Middle East Respiratory Syndrome coronavirus Shauna Milne-Price, Kerri L. Miazgowicz, Vincent J. Munster On September 20, 2012, a Saudi Arabian physician reported the isolation of a novel coronavirus from a patient with pneumonia on ProMED mail. Within a few days, the same virus was detected in a Qatari patient receiving intensive care in a London hospital, a situation reminiscent of the role air travel played in the spread of severe acute respiratory syndrome coronavirus (SARS CoV) in 2002. SARS CoV... DOI: 10.1111/2049-632x.12166 |
Visibilidad | the emergence of the Middle East Respiratory Syndrome coronavirus | 0.08 | 001-460-168-050-735 | Pathogens and Disease | 2018-05-12 | 0.8 | |
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The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes Hao Zhang, Zijian Kang, Haiyi Gong, et al. Since December 2019, a newly identified coronavirus (2019 novel coronavirus, 2019-nCov) is causing outbreak of pneumonia in one of largest cities, Wuhan, in Hubei province of China and has draw significant public health attention. The same as severe acute respiratory syndrome coronavirus (SARS-CoV), 2019-nCov enters into host cells via cell receptor angiotensin converting enzyme II (ACE2). In orde... DOI: 10.1101/2020.01.30.927806 [PDF] |
Visibilidad | The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes | 0.08 | 000-851-047-428-254 | bioRxiv | 2020-02-07 | 0.8 | |
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Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity Stefanie Gierer, Marcel A. Müller, Adeline Heurich, et al. MiddleEastrespiratorysyndromecoronavirus(MERS-CoV)infectionisassociatedwithahighcase-fatalityrate,and the potential pandemic spread of the virus is a public health concern. The spike protein of MERS-CoV(MERS-S) facilitates viral entry into host cells, which depends on activation of MERS-S by cellular proteases.Proteolytic activation of MERS-S during viral uptake into target cells has been demonstr... DOI: 10.1093/infdis/jiu407 |
Visibilidad | Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity | 0.08 | 084-968-559-298-461 | The Journal of Infectious Diseases | 2018-05-12 | 0.8 | |
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Comparative Analysis of 22 Coronavirus HKU1 Genomes Reveals a Novel Genotype and Evidence of Natural Recombination in Coronavirus HKU1 Patrick C. Y. Woo, Susanna K. P. Lau, Cyril C. Y. Yip, et al. We sequenced and compared the complete genomes of 22 strains of coronavirus HKU1 (CoV HKU1) obtained from nasopharyngeal aspirates of patients with respiratory tract infections over a 2-year period. Phylogenetic analysis of 24 putative proteins and polypeptides showed that the 22 CoV HKU1 strains fell into three clusters (genotype A, 13 strains; genotype B, 3 strains and genotype C, 6 strains). Ho... DOI: 10.1128/jvi.00509-06 |
Visibilidad | Comparative Analysis of 22 Coronavirus HKU1 Genomes Reveals a Novel Genotype and Evidence of Natural Recombination in Coronavirus HKU1 | 0.08 | 013-000-803-258-286 | Journal of Virology | 2018-05-12 | 0.8 | |
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Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study Ziad A. Memish, Jaffar A. Al-Tawfiq, Hatem Q. Makhdoom, et al. The Saudi Arabian Ministry of Health implemented a pro-active surveillance programme for Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV). We report MERS-CoV data from 5065 Kingdom of Saudi Arabia individuals who were screened for MERS-CoV over a 12-month period. From 1 October 2012 to 30 September 2013, demographic and clinical data were prospectively collected from all laboratory f... DOI: 10.1111/1469-0691.12562 |
Visibilidad | Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study | 0.08 | 009-436-099-437-127 | Clinical Microbiology and Infection | 2018-05-12 | 0.8 | |
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First Case of 2019 Novel Coronavirus in the United States Michelle Holshue, Chas DeBolt, Scott Lindquist, et al. Summary An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection ... DOI: 10.1056/nejmoa2001191 |
Visibilidad | First Case of 2019 Novel Coronavirus in the United States | 0.08 | 117-641-457-355-454 | The New England Journal of Medicine | 2020-02-06 | 0.8 | |
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Evolutionary Trajectory for the Emergence of Novel Coronavirus SARS-CoV-2 Saif ur Rehman, Laiba Shafique, Awais Ihsan, et al. DOI: 10.3390/pathogens9030240 |
Visibilidad | Evolutionary Trajectory for the Emergence of Novel Coronavirus SARS-CoV-2 | 0.07 | 006-170-782-853-163 | Pathogens | 2020-03-29 | 0.7 | |
| 33-0.07 | New | Visibilidad | Covid-19: what treatments are being investigated? | 0.07 | 050-163-234-742-411 | BMJ | 2020-03-29 | 0.7 | ||
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Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality Robert O. Bonow, Gregg C. Fonarow, Patrick T. O’Gara, et al. DOI: 10.1001/jamacardio.2020.1105 |
Visibilidad | Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality | 0.07 | 108-319-260-474-984 | JAMA Cardiology | 2020-03-29 | 0.7 | |
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Characterization of viral proteins encoded by the SARS-coronavirus genome Yee-Joo Tan, Seng Gee Lim, Wanjin Hong Abstract A new disease, termed severe acute respiratory syndrome (SARS), emerged at the end of 2002 and caused profound disturbances in over 30 countries worldwide in 2003. A novel coronavirus was identified as the aetiological agent of SARS and the 30 kb viral genome was deciphered with unprecedented speed in a coordinated manner by the global community. Since then, much progress has been made in... DOI: 10.1016/j.antiviral.2004.10.001 |
Visibilidad | Characterization of viral proteins encoded by the SARS-coronavirus genome | 0.07 | 103-028-304-432-726 | Antiviral Research | 2018-05-12 | 0.7 | |
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The severe acute respiratory syndrome coronavirus 3a is a novel structural protein. Shuo Shen, Pi-Shiu Lin, Yu-Chan Chao, et al. The severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein is one of the opening reading frames in the viral genome with no homologue in other known coronaviruses. Expression of the 3a protein has been demonstrated during both in vitro and in vivo infection. Here we present biochemical data to show that 3a is a novel coronavirus structural protein. 3a was detected in virions purified ... DOI: 10.1016/j.bbrc.2005.02.153 |
Visibilidad | The severe acute respiratory syndrome coronavirus 3a is a novel structural protein. | 0.07 | 001-275-376-346-421 | Biochemical and Biophysical Research Communications | 2018-05-12 | 0.7 | |
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Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003 N. S. Zhong, Bo-Jian Zheng, Y. M. Li, et al. Summary Background An epidemic of severe acute respiratory syndrome (SARS) has been associated with an outbreak of atypical pneumonia originating in Guangdong Province, People's Republic of China. We aimed to identify the causative agent in the Guangdong outbreak and describe the emergence and spread of the disease within the province. Methods We analysed epidemiological information and collected ... DOI: 10.1016/s0140-6736(03)14630-2 |
Visibilidad | Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003 | 0.07 | 035-719-660-892-049 | The Lancet | 2018-05-12 | 0.7 | |
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Coronaviral hypothetical and structural proteins were found in the intestinal surface enterocytes and pneumocytes of severe acute respiratory syndrome (SARS) Wai S. Chan, Chun Wu, Sammy C.S. Chow, et al. Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease that haunted the world from November 2002 to July 2003. Little is known about the biology and pathophysiology of the novel coronavirus that causes SARS. The tissue and cellular distributions of coronaviral hypothetical and structural proteins in SARS were investigated. Antibodies against the hypothetical (SARS 3a, 3b, ... DOI: 10.1038/modpathol.3800439 |
Visibilidad | Coronaviral hypothetical and structural proteins were found in the intestinal surface enterocytes and pneumocytes of severe acute respiratory syndrome (SARS) | 0.06 | 018-877-233-968-632 | Modern Pathology | 2018-05-12 | 0.6 | |
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Clinical Characteristics of Coronavirus Disease 2019 in China Wei-jie Guan, Zheng-yi Ni, Yu Hu, et al. Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of... DOI: 10.1056/nejmoa2002032 |
Visibilidad | Clinical Characteristics of Coronavirus Disease 2019 in China | 0.06 | 049-210-365-290-957 | The New England Journal of Medicine | 2020-03-05 | 0.6 | |
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Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia Feng Pan, Tianhe Ye, Peng Sun, et al. Background Chest CT is used to assess the severity of lung involvement in COVID-19 pneumonia. Purpose To determine the change in chest CT findings associated with COVID-19 pneumonia from initial di... DOI: 10.1148/radiol.2020200370 |
Visibilidad | Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia | 0.06 | 117-851-201-366-235 | Radiology | 2020-02-21 | 0.6 | |
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Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels Danielle R. Adney, Neeltje van Doremalen, Vienna R. Brown, et al. In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isolate ... DOI: 10.3201/eid2012.141280 |
Visibilidad | Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels | 0.06 | 016-721-175-170-660 | Emerging Infectious Diseases | 2018-05-12 | 0.6 | |
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Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections Ziad A. Memish, Alimuddin Zumla, Rafat F. Alhakeem, et al. A human coronavirus, called the Middle East respiratory syndrome coronavirus (MERS-CoV), was first identified in September 2012 in samples obtained from a Saudi Arabian businessman who died from acute respiratory failure. Since then, 49 cases of infections caused by MERS-CoV (previously called a novel coronavirus) with 26 deaths have been reported to date. In this report, we describe a family case... DOI: 10.1056/nejmoa1303729 |
Visibilidad | Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections | 0.06 | 126-216-458-383-35X | The New England Journal of Medicine | 2018-05-12 | 0.6 | |
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Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention Zunyou Wu, Jennifer M. McGoogan The Chinese Center for Disease Control and Prevention recently published the largest case series to date of coronavirus disease 2019 (COVID-19) in mainland China (72 314 cases, updated through February 11, 2020). This Viewpoint summarizes key findings from this report and discusses emerging understanding of and lessons from the COVID-19 epidemic. DOI: 10.1001/jama.2020.2648 |
Visibilidad | Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention | 0.05 | 041-252-693-988-726 | JAMA | 2020-02-25 | 0.5 | |
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Therapeutic options for the treatment of 2019-novel coronavirus: An evidence-based approach. Phulen Sarma, Manisha Prajapat, Pramod Avti, et al. |
Visibilidad | Therapeutic options for the treatment of 2019-novel coronavirus: An evidence-based approach. | 0.05 | 123-494-241-257-265 | Indian journal of pharmacology | 2020-03-27 | 0.5 | |
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Responding to COVID-19: How to Navigate a Public Health Emergency Legally and Ethically LAWRENCE O. GOSTIN, ERIC A. FRIEDMAN, SARAH A. WETTER DOI: 10.1002/hast.1090 |
Visibilidad | Responding to COVID-19: How to Navigate a Public Health Emergency Legally and Ethically | 0.05 | 112-470-150-380-035 | Hastings Center Report | 2020-03-29 | 0.5 | |
| 46-0.05 | New | Visibilidad | Coronavirus uses as binding site in humans angiotensin-converting enzyme 2 functional receptor that is involved in arterial blood pressure control and fibrotic response to damage and is a drug target in cardiovascular disease. Is this just a phylogenetic | 0.05 | 132-799-722-728-818 | Journal of Medical Virology | 2020-03-29 | 0.5 | ||
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Mental Health and Psychological Intervention Amid COVID-19 Outbreak: Perspectives from South Korea Sun Jae Jung, Jin Yong Jun DOI: 10.3349/ymj.2020.61.4.271 |
Visibilidad | Mental Health and Psychological Intervention Amid COVID-19 Outbreak: Perspectives from South Korea | 0.05 | 136-892-563-610-979 | Yonsei Medical Journal | 2020-03-29 | 0.5 | |
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Travel restrictions violate international law Benjamin Mason Meier, Roojin Habibi, Y. Tony Yang DOI: 10.1126/science.abb6950 |
Visibilidad | Travel restrictions violate international law | 0.05 | 090-312-582-710-544 | Science | 2020-03-29 | 0.5 | |
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Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein Ke Xu, Bo-Jian Zheng, Rong Zeng, et al. Eight accessory proteins have been identified in severe acute respiratory syndrome-associated coronavirus (SARS-CoV). They are believed to play roles in the viral life cycle and may contribute to the pathogenesis and virulence. ORF9b as one of these accessory proteins is located in subgenomic mRNA9 and encodes a 98 amino acid protein. However, whether 9b protein is a structural component of SARS-C... DOI: 10.1016/j.virol.2009.03.032 |
Visibilidad | Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein | 0.05 | 089-197-571-997-352 | Virology | 2018-05-11 | 0.5 | |
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The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein Purnima Kumar, Vithiagaran Gunalan, Boping Liu, et al. Abstract Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) caused a severe outbreak in several regions of the world in 2003. The SARS-CoV genome is predicted to contain 14 functional open reading frames (ORFs). The first ORF (1a and 1b) encodes a large polyprotein that is cleaved into nonstructural proteins (nsp). The other ORFs encode for four structural proteins (spike, membrane, n... DOI: 10.1016/j.virol.2007.04.029 |
Visibilidad | The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein | 0.05 | 079-964-139-501-348 | Virology | 2018-05-12 | 0.5 | |
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A putative diacidic motif in the SARS-CoV ORF6 protein influences its subcellular localization and suppression of expression of co-transfected expression constructs Vithiagaran Gunalan, Ali Mirazimi, Yee-Joo Tan Background The ORF6 protein is one of the eight accessory proteins of the severe acute respiratory syndrome coronavirus (SARS-CoV). Numerous properties of ORF6 have been documented and this study focuses on two of these, namely, its ability to suppress the expression of co-transfected expression constructs and its subcellular localization to vesicular structures. DOI: 10.1186/1756-0500-4-446 |
Visibilidad | A putative diacidic motif in the SARS-CoV ORF6 protein influences its subcellular localization and suppression of expression of co-transfected expression constructs | 0.05 | 081-749-213-064-984 | BMC Research Notes | 2018-05-11 | 0.5 | |
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SARS: lessons learned from other coronaviruses. Sonia Navas-Martin, Susan R. Weiss The identification of a new coronavirus as the etiological agent of severe acute respiratory syndrome (SARS) has evoked much new interest in the molecular biology and pathogenesis of coronaviruses. This review summarizes present knowledge on coronavirus molecular biology and pathogenesis with particular emphasis on mouse hepatitis virus (MHV). MHV, a member of coronavirus group 2, is a natural pat... DOI: 10.1089/088282403771926292 |
Visibilidad | SARS: lessons learned from other coronaviruses. | 0.05 | 031-639-327-965-309 | Viral Immunology | 2018-05-12 | 0.5 | |
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Adenovirus-mediated expression of the C-terminal domain of SARS-CoV spike protein is sufficient to induce apoptosis in Vero E6 cells. Ken Y.C. Chow, Yin Shan Yeung, Chung-Chau Hon, et al. The pro-apoptotic properties of severe acute respiratory syndrome coronavirus (SARS-CoV) structural proteins were studied in vitro. By monitoring apoptosis indicators including chromatin condensation, cellular DNA fragmentation and cell membrane asymmetry, we demonstrated that the adenovirus-mediated over-expression of SARS-CoV spike (S) protein and its C-terminal domain (S2) induce apoptosis in V... DOI: 10.1016/j.febslet.2005.10.065 |
Visibilidad | Adenovirus-mediated expression of the C-terminal domain of SARS-CoV spike protein is sufficient to induce apoptosis in Vero E6 cells. | 0.05 | 092-293-801-133-129 | FEBS Letters | 2018-05-12 | 0.5 | |
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Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS) Gary M-K Tse, Ka-Fai To, Paul K.S. Chan, et al. Background: Severe acute respiratory syndrome (SARS) became a worldwide outbreak with a mortality of 9.2%. This new human emergent infectious disease is dominated by severe lower respiratory illness and is aetiologically linked to a new coronavirus (SARS-CoV). Methods: Pulmonary pathology and clinical correlates were investigated in seven patients who died of SARS in whom there was a strong epide... DOI: 10.1136/jcp.2003.013276 |
Visibilidad | Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS) | 0.05 | 014-515-411-569-375 | Journal of Clinical Pathology | 2018-05-12 | 0.5 | |
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Characterization of a Unique Group-Specific Protein (U122) of the Severe Acute Respiratory Syndrome Coronavirus Burtram C. Fielding, Yee-Joo Tan, Shen Shuo, et al. A novel coronavirus (CoV) has been identified as the etiological agent of severe acute respiratory syndrome (SARS). The SARS-CoV genome encodes the characteristic essential CoV replication and structural proteins. Additionally, the genome contains six group-specific open reading frames (ORFs) larger than 50 amino acids, with no known homologues. As with the group-specific genes of the other CoVs, ... DOI: 10.1128/jvi.78.14.7311-7318.2004 |
Visibilidad | Characterization of a Unique Group-Specific Protein (U122) of the Severe Acute Respiratory Syndrome Coronavirus | 0.05 | 012-801-657-103-406 | Journal of Virology | 2018-05-12 | 0.5 | |
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Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT Burtram C. Fielding, Vithiagaran Gunalan, Timothy H. P. Tan, et al. Severe acute respiratory syndrome coronavirus (SARS-CoV) 7a is an accessory protein with no known homologues. In this study, we report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing protein (SGT). SARS-CoV 7a and human SGT interaction was identified using a two-hybrid system screen and confirmed with interaction screens in cell culture and cellular co... DOI: 10.1016/j.bbrc.2006.03.091 |
Visibilidad | Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT | 0.05 | 105-476-160-932-984 | Biochemical and Biophysical Research Communications | 2018-05-12 | 0.5 | |
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Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Joseph T. Wu, Kathy Leung, Gabriel M. Leung Summary Background Since Dec 31, 2019, the Chinese city of Wuhan has reported an outbreak of atypical pneumonia caused by the 2019 novel coronavirus (2019-nCoV). Cases have been exported to other Chinese cities, as well as internationally, threatening to trigger a global outbreak. Here, we provide an estimate of the size of the epidemic in Wuhan on the basis of the number of cases exported from Wu... DOI: 10.1016/s0140-6736(20)30260-9 |
Visibilidad | Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study | 0.05 | 063-014-267-382-902 | The Lancet | 2020-02-06 | 0.5 | |
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Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate Fernando Almazán, Marta L. DeDiego, Isabel Sola, et al. ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging coronavirus infecting humans that is associated with acute pneumonia, occasional renal failure, and a high mortality rate and is considered a threat to public health. The construction of a full-length infectious cDNA clone of the MERS-CoV genome in a bacterial artificial chromosome is reported here, providing a reverse... DOI: 10.1128/mbio.00650-13 |
Visibilidad | Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate | 0.05 | 057-127-923-286-534 | Mbio | 2018-05-12 | 0.5 | |
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SARS-associated coronavirus. Kathryn V. Holmes The discovery that a novel coronavirus is the probable cause of the newly recognized severe acute respiratory syndrome (SARS), reported by Ksiazek et al. (pages 1953–1966), Drosten et al. (pages 1967–1976), and Peiris et al.1 provides a dramatic example of an emerging coronavirus disease in humans, described by Poutanen et al. (pages 1995–2005), Tsang et al. (pages 1977–1985), and Lee et al. (page... DOI: 10.1056/nejmp030078 |
Visibilidad | SARS-associated coronavirus. | 0.05 | 156-410-219-615-528 | The New England Journal of Medicine | 2018-05-12 | 0.5 | |
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Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study. Jaffar A. Al-Tawfiq, Hisham Momattin, Jean G. Dib, et al. Summary Background The Middle East respiratory syndrome coronavirus (MERS-CoV) has been reported to have a high case-fatality rate. Currently, there is no specific therapy or vaccine with proven effectiveness for MERS-CoV infections. Methods A combination of ribavirin and interferon therapy was used for the treatment of five MERS-CoV-positive patients. We reviewed the therapeutic schedule and the ... DOI: 10.1016/j.ijid.2013.12.003 |
Visibilidad | Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study. | 0.05 | 073-663-856-907-01X | International Journal of Infectious Diseases | 2018-05-12 | 0.5 | |
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Genomic Characterisation and Epidemiology of 2019 Novel Coronavirus: Implications for Virus Origins and Receptor Binding Roujian Lu, Xiang Zhao, Juan Li, et al. Summary Background In late December, 2019, patients presenting with viral pneumonia due to an unidentified microbial agent were reported in Wuhan, China. A novel coronavirus was subsequently identified as the causative pathogen, provisionally named 2019 novel coronavirus (2019-nCoV). As of Jan 26, 2020, more than 2000 cases of 2019-nCoV infection have been confirmed, most of which involved people ... DOI: 10.1016/s0140-6736(20)30251-8 |
Visibilidad | Genomic Characterisation and Epidemiology of 2019 Novel Coronavirus: Implications for Virus Origins and Receptor Binding | 0.05 | 024-982-561-486-693 | The Lancet | 2020-02-06 | 0.5 | |
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Importation and Human-to-Human Transmission of a Novel Coronavirus in Vietnam Lan T. Phan, Thuong Vu Nguyen, Quang C. Luong, et al. Human-to-Human Coronavirus Transmission in Vietnam The authors describe transmission of 2019-nCoV from a father, who had flown with his wife from Wuhan to Hanoi, to the son, who met his father and ... DOI: 10.1056/nejmc2001272 |
Visibilidad | Importation and Human-to-Human Transmission of a Novel Coronavirus in Vietnam | 0.05 | 013-822-140-463-176 | The New England Journal of Medicine | 2020-02-06 | 0.5 | |
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Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019-nCoV) outbreak Benjamin J. Cowling, Gabriel M. Leung DOI: 10.2807/1560-7917.es.2020.25.6.2000110 |
Visibilidad | Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019-nCoV) outbreak | 0.04 | 020-653-905-150-50X | Eurosurveillance | 2020-02-21 | 0.4 | |
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Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 Jianhui Nie, Qianqian Li, Jiajing Wu, et al. DOI: 10.1080/22221751.2020.1743767 |
Visibilidad | Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 | 0.04 | 127-859-870-425-756 | Emerging Microbes & Infections | 2020-03-27 | 0.4 | |
| 65-0.04 | New | Visibilidad | Exercising Heart and Head in Managing Coronavirus Disease 2019 in Wuhan | 0.04 | 180-426-932-736-719 | JAMA Network Open | 2020-03-27 | 0.4 | ||
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Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis Wei-jie Guan, Wen-hua Liang, Yi Zhao, et al. DOI: 10.1183/13993003.00547-2020 |
Visibilidad | Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis | 0.04 | 044-277-668-258-449 | European Respiratory Journal | 2020-03-28 | 0.4 | |
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Clinical and CT features of early-stage patients with COVID-19: a retrospective analysis of imported cases in Shanghai, China Shuyi Yang, Yuxin Shi, Hongzhou Lu, et al. DOI: 10.1183/13993003.00407-2020 |
Visibilidad | Clinical and CT features of early-stage patients with COVID-19: a retrospective analysis of imported cases in Shanghai, China | 0.04 | 159-486-882-997-438 | European Respiratory Journal | 2020-03-28 | 0.4 | |
| 68-0.04 | New | Visibilidad | Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia | 0.04 | 179-813-259-883-819 | Journal of Thrombosis and Haemostasis | 2020-03-28 | 0.4 | ||
| 69-0.04 | New | Visibilidad | An Acute Respiratory Infection Runs Into the Most Common Noncommunicable Epidemic—COVID-19 and Cardiovascular Diseases | 0.04 | 195-048-023-868-414 | JAMA Cardiology | 2020-03-28 | 0.4 | ||
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Renin-Angiotensin System Blockers and the COVID-19 Pandemic A.H. Jan Danser, Murray Epstein, Daniel Batlle DOI: 10.1161/hypertensionaha.120.15082 |
Visibilidad | Renin-Angiotensin System Blockers and the COVID-19 Pandemic | 0.04 | 008-940-459-243-518 | Hypertension | 2020-03-28 | 0.4 | |
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges Chih-Cheng Lai, Tzu-Ping Shih, Wen-Chien Ko, et al. ABSTRACT The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; previously provisionally named 2019 novel coronavirus or 2019-nCoV) disease (COVID-19) in China at the end of 2019 has caused a large global outbreak and is a major public health issue. As of 11 February 2020, data from the World Health Organization (WHO) have shown that more than 43 000 confirmed cases have bee... DOI: 10.1016/j.ijantimicag.2020.105924 |
Visibilidad | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges | 0.04 | 116-195-781-737-645 | International Journal of Antimicrobial Agents | 2020-02-21 | 0.4 | |
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Severe acute respiratory syndrome-related coronavirus - The species and its viruses, a statement of the Coronavirus Study Group Alexander E. Gorbalenya, Susan C. Baker, Ralph S. Baric, et al. The present outbreak of lower respiratory tract infections, including respiratory distress syndrome, is the third spillover, in only two decades, of an animal coronavirus to humans resulting in a major epidemic. Here, the Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses, which is responsible for developing the official classification of viruses and taxa naming (t... DOI: 10.1101/2020.02.07.937862 [PDF] |
Visibilidad | Severe acute respiratory syndrome-related coronavirus - The species and its viruses, a statement of the Coronavirus Study Group | 0.04 | 144-781-526-712-421 | bioRxiv | 2020-02-21 | 0.4 | |
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Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan Jasper F. W. Chan, Kin-Hang Kok, Zheng Zhu, et al. ABSTRACTA mysterious outbreak of atypical pneumonia in late 2019 was traced to a seafood wholesale market in Wuhan of China. Within a few weeks, a novel coronavirus tentatively named as 2019 novel ... DOI: 10.1080/22221751.2020.1719902 |
Visibilidad | Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan | 0.04 | 089-914-905-831-950 | Emerging microbes & infections | 2020-02-06 | 0.4 | |
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Clinical characteristics of 2019 novel coronavirus infection in China Wei-jie Guan, Zheng-yi Ni, Yu Hu, et al. Background: Since December 2019, acute respiratory disease (ARD) due to 2019 novel coronavirus (2019-nCoV) emerged in Wuhan city and rapidly spread throughout China. We sought to delineate the clinical characteristics of these cases. Methods: We extracted the data on 1,099 patients with laboratory-confirmed 2019-nCoV ARD from 552 hospitals in 31 provinces/provincial municipalities through January ... DOI: 10.1101/2020.02.06.20020974 [PDF] |
Visibilidad | Clinical characteristics of 2019 novel coronavirus infection in China | 0.04 | 016-332-382-913-413 | medRxiv | 2020-02-10 | 0.4 | |
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Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020 Jantien A. Backer, Don Klinkenberg, Jacco Wallinga A novel coronavirus (2019-nCoV) is causing an outbreak of viral pneumonia that started in Wuhan, China. Using the travel history and symptom onset of 88 confirmed cases that were detected outside Wuhan in the early outbreak phase, we estimate the mean incubation period to be 6.4 days (95% credible interval: 5.6–7.7), ranging from 2.1 to 11.1 days (2.5th to 97.5th percentile). These values should h... DOI: 10.2807/1560-7917.es.2020.25.5.2000062 |
Visibilidad | Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020 | 0.04 | 083-827-415-697-214 | Eurosurveillance | 2020-02-07 | 0.4 | |
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Profiles of Antibody Responses against Severe Acute Respiratory Syndrome Coronavirus Recombinant Proteins and Their Potential Use as Diagnostic Markers Yee-Joo Tan, Phuay-Yee Goh, Burtram C. Fielding, et al. A new coronavirus (severe acute respiratory syndrome coronavirus [SARS-CoV]) has been identified to be the etiological agent of severe acute respiratory syndrome. Given the highly contagious and acute nature of the disease, there is an urgent need for the development of diagnostic assays that can detect SARS-CoV infection. For determination of which of the viral proteins encoded by the SARS-CoV ge... DOI: 10.1128/cdli.11.2.362-371.2004 |
Visibilidad | Profiles of Antibody Responses against Severe Acute Respiratory Syndrome Coronavirus Recombinant Proteins and Their Potential Use as Diagnostic Markers | 0.04 | 027-497-672-107-166 | Clinical and Vaccine Immunology | 2018-05-12 | 0.4 | |
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The nsp9 replicase protein of SARS-coronavirus, structure and functional insights. Geoff Sutton, Elizabeth E. Fry, Lester G. Carter, et al. As part of a high-throughput structural analysis of SARS-coronavirus (SARS-CoV) proteins, we have solved the structure of the non-structural protein 9 (nsp9). This protein, encoded by ORF1a, has no designated function but is most likely involved with viral RNA synthesis. The protein comprises a single β-barrel with a fold previously unseen in single domain proteins. The fold superficially resemble... DOI: 10.1016/j.str.2004.01.016 |
Visibilidad | The nsp9 replicase protein of SARS-coronavirus, structure and functional insights. | 0.04 | 000-037-106-895-586 | Structure | 2018-05-11 | 0.4 | |
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Drug targets for corona virus: A systematic review. Manisha Prajapat, Phulen Sarma, Nishant Shekhar, et al. The 2019-novel coronavirus (nCoV) is a major source of disaster in the 21th century. However, the lack of specific drugs to prevent/treat an attack is a major need at this current point of time. In this regard, we conducted a systematic review to identify major druggable targets in coronavirus (CoV). We searched PubMed and RCSB database with keywords HCoV, NCoV, corona virus, SERS-CoV, ... |
Visibilidad | Drug targets for corona virus: A systematic review. | 0.03 | 083-782-614-549-701 | Indian journal of pharmacology | 2020-03-27 | 0.3 | |
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SARS-CoV-2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability Vinicio Armijos-Jaramillo, Justin Yeager, Claire Muslin, et al. DOI: 10.1101/2020.03.21.001933 |
Visibilidad | SARS-CoV-2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability | 0.03 | 046-670-017-629-959 | 2020-03-27 | 0.3 | ||
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Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington Temet M. McMichael, Dustin W. Currie, Shauna Clark, et al. DOI: 10.1056/nejmoa2005412 |
Visibilidad | Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington | 0.03 | 006-935-830-131-58X | New England Journal of Medicine | 2020-03-29 | 0.3 | |
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Elevated plasmin(ogen) as a common risk factor for COVID-19 susceptibility Hong-Long Ji, Runzhen Zhao, Sadis Matalon, et al. DOI: 10.1152/physrev.00013.2020 |
Visibilidad | Elevated plasmin(ogen) as a common risk factor for COVID-19 susceptibility | 0.03 | 131-524-848-495-731 | Physiological Reviews | 2020-03-29 | 0.3 | |
| 712-0.03 | New | Visibilidad | Might the many positive COVID19 subjects in Italy have been caused by resident bat-derived zoonotic β-coronaviruses instead of the Wuhan (China) outbreak? | 0.03 | 036-019-105-167-269 | Journal of Medical Virology | 2020-03-29 | 0.3 | ||
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Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore Barnaby Young, Ong Swx, Shirin Kalimuddin, et al. Importance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019 and has spread globally with sustained human-to-human transmission outside China. Objective To report the initial experience in Singapore with the epidemiologic investigation of this outbreak, clinical features, and management. Design, Setting, and Participants Descriptive case series ... DOI: 10.1001/jama.2020.3204 |
Visibilidad | Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore | 0.03 | 075-567-610-028-19X | JAMA | 2020-03-05 | 0.3 | |
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Coronavirus Disease 2019 (COVID-19): A Perspective from China Zi Yue Zu, Meng Di Jiang, Peng Peng Xu, et al. Abstract In December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection occurred in Wuhan, Hubei Province, China and spread across China and beyond. On Febr... DOI: 10.1148/radiol.2020200490 |
Visibilidad | Coronavirus Disease 2019 (COVID-19): A Perspective from China | 0.03 | 039-203-752-503-619 | Radiology | 2020-02-25 | 0.3 | |
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Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic? Jasper F. W. Chan, Kenneth S. M. Li, Kelvin K. W. To, et al. Summary Fouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named "human betacoronavirus 2c EMC/2012 (HCoV-EMC)" from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and ... DOI: 10.1016/j.jinf.2012.10.002 |
Visibilidad | Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic? | 0.03 | 027-359-098-622-423 | Journal of Infection | 2018-05-11 | 0.3 | |
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Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection Adam Bernheim, Xueyan Mei, Mingqian Huang, et al. Abstract In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were... DOI: 10.1148/radiol.2020200463 |
Visibilidad | Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection | 0.03 | 108-237-285-451-683 | Radiology | 2020-02-21 | 0.3 | |
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Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China Min Wei, Jingping Yuan, Yu Liu, et al. Since December 8, 2019, an epidemic of coronavirus disease 2019 (COVID-19) has spread rapidly. As of February 6, 2020, China reported 31 211 confirmed cases of COVID-19 and 637 fatalities.Previous studies suggest that COVID-19 is more likely to infect older adult men, particularly those with chronic comorbidities. Few infections in children have been reported. We identified all infected infants in... DOI: 10.1001/jama.2020.2131 |
Visibilidad | Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China | 0.03 | 054-649-457-055-286 | JAMA | 2020-02-21 | 0.3 | |
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Neutralizing antibody and protective immunity to SARS coronavirus infection of mice induced by a soluble recombinant polypeptide containing an N-terminal segment of the spike glycoprotein. Himani Bisht, Anjeanette Roberts, Leatrice Vogel, et al. A secreted, glycosylated polypeptide containing amino acids 14 to 762 of the SARS coronavirus (SARS-CoV) spike protein and a polyhistidine tag was expressed in recombinant baculovirus-infected insect cells. Mice received the affinity-purified protein with either a saponin (QS21) or a Ribi (MPL + TDM) adjuvant subcutaneously and were challenged intranasally with SARS-CoV. Both regimens induced bind... DOI: 10.1016/j.virol.2005.01.042 |
Visibilidad | Neutralizing antibody and protective immunity to SARS coronavirus infection of mice induced by a soluble recombinant polypeptide containing an N-terminal segment of the spike glycoprotein. | 0.03 | 016-375-522-782-380 | Virology | 2018-05-12 | 0.3 | |
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Detection of alpha and betacoronaviruses in multiple Iberian bat species Ana Falcón, Sonia Vázquez-Morón, Inmaculada Casas, et al. Bat coronaviruses (CoV) are putative precursors of the severe acute respiratory syndrome (SARS) CoV and other CoV that crossed the species barrier from zoonotic reservoirs into the human population. To determine the presence and distribution of CoV in Iberian bats, 576 individuals of 26 different bat species were captured in 13 locations in Spain. We report for the first time the presence of 14 co... DOI: 10.1007/s00705-011-1057-1 |
Visibilidad | Detection of alpha and betacoronaviruses in multiple Iberian bat species | 0.03 | 095-648-497-026-239 | Archives of Virology | 2018-05-11 | 0.3 | |
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A new coronavirus associated with human respiratory disease in China Fan Wu, Su Zhao, Bin Yu, et al. Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health1–3. Despite intense research efforts, how, when and where new diseases appear are still a source of considerable uncertainty. A severe respiratory disease was recently reported in Wuhan, Hubei province, China. As of 25 January 2020, at least 1,975 cases had... DOI: 10.1038/s41586-020-2008-3 |
Visibilidad | A new coronavirus associated with human respiratory disease in China | 0.03 | 005-646-681-950-532 | Nature | 2020-02-06 | 0.3 | |
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Coronavirus HKU1 and Other Coronavirus Infections in Hong Kong Susanna K. P. Lau, Patrick C. Y. Woo, Cyril C. Y. Yip, et al. We have recently described the discovery of a novel coronavirus, coronavirus HKU1 (CoV-HKU1), associated with community-acquired pneumonia. However, the clinical spectrum of disease and the epidemiology of CoV-HKU1 infections in relation to infections with other respiratory viruses are unknown. In this 12-month prospective study, 4,181 nasopharyngeal aspirates from patients with acute respiratory ... DOI: 10.1128/jcm.02614-05 |
Visibilidad | Coronavirus HKU1 and Other Coronavirus Infections in Hong Kong | 0.03 | 016-455-765-080-527 | Journal of Clinical Microbiology | 2018-05-12 | 0.3 | |
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Amino Acids 270 to 510 of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Are Required for Interaction with Receptor Gregory J. Babcock, Diana J. Esshaki, William D. Thomas, et al. A novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV), has recently been identified as the causative agent of severe acute respiratory syndrome (SARS). SARS-CoV appears similar to other coronaviruses in both virion structure and genome organization. It is known for other coronaviruses that the spike (S) glycoprotein is required for both viral attachment to permissive cells ... DOI: 10.1128/jvi.78.9.4552-4560.2004 |
Visibilidad | Amino Acids 270 to 510 of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Are Required for Interaction with Receptor | 0.03 | 025-734-705-876-388 | Journal of Virology | 2018-05-12 | 0.3 | |
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Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany Camilla Rothe, Mirjam Schunk, Peter Sothmann, et al. 2019-nCoV Transmission from Asymptomatic Patient In this report, investigators in Germany detected the spread of the novel coronavirus (2019-nCoV) from a person who had recently traveled from China... DOI: 10.1056/nejmc2001468 |
Visibilidad | Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany | 0.02 | 071-164-622-563-358 | The New England Journal of Medicine | 2020-02-06 | 0.2 | |
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Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak Annelies Wilder-Smith, David O. Freedman Community containment includes measures that range from increasing social distancing to coummunity-wide quarantine. Whether these measures will be sufficient to control 2019-ncov depends on addressing some unanswered questions. DOI: 10.1093/jtm/taaa020 |
Visibilidad | Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak | 0.02 | 001-775-786-655-463 | Journal of Travel Medicine | 2020-02-10 | 0.2 | |
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The Extent of Transmission of Novel Coronavirus in Wuhan, China, 2020 Hiroshi Nishiura, Sung-mok Jung, Natalie M. Linton, et al. A cluster of pneumonia cases linked to a novel coronavirus (2019-nCoV) was reported by China in late December 2019. Reported case incidence has now reached the hundreds, but this is likely an underestimate. As of 24 January 2020, with reports of thirteen exportation events, we estimate the cumulative incidence in China at 5502 cases (95% confidence interval: 3027, 9057). The most plausible number ... DOI: 10.3390/jcm9020330 |
Visibilidad | The Extent of Transmission of Novel Coronavirus in Wuhan, China, 2020 | 0.02 | 148-573-541-549-860 | Journal of Clinical Medicine | 2020-01-26 | 0.2 | |
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Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Harrison X Bai, Ben Hsieh, Zeng Xiong, et al. Background Despite its high sensitivity in diagnosing COVID-19 in a screening population, chest CT appearances of COVID 19 pneumonia are thought to be non-specific. Purpose To assess the performance of United States (U.S.) and Chinese radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Methods A total of 219 patients with both positive COVID-19 by RT-PCR and abnormal chest C... DOI: 10.1148/radiol.2020200823 |
Visibilidad | Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT. | 0.02 | 034-462-900-246-779 | Radiology | 2020-03-23 | 0.2 | |
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Middle East respiratory syndrome: pathogenesis and therapeutic developments. Hani Choudhry, Muhammed A Bakhrebah, Wesam H Abdulaal, et al. The first case of Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in the year 2012, which spread rapidly and increased to more than 2200 in 2018. This highly pathogenic virus with high mortality rate is among one of the major public health concerns. Saudi Arabia remains to be the most affected region with the majority of MERS-CoV cases, and currently, no effective drugs and ... |
Visibilidad | Middle East respiratory syndrome: pathogenesis and therapeutic developments. | 0.02 | 164-806-251-625-292 | Future virology | 2020-03-27 | 0.2 | |
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Public awareness of coronavirus in Al-Jouf region, Saudi Arabia. Hanaa Zakaria Nooh, Rawan Humaidy Alshammary, Jomanh Mohammed Alenezy, et al. |
Visibilidad | Public awareness of coronavirus in Al-Jouf region, Saudi Arabia. | 0.02 | 172-529-541-911-841 | Zeitschrift fur Gesundheitswissenschaften = Journal of public health | 2020-03-27 | 0.2 | |
| 729-0.02 | New | Visibilidad | 2019 Novel Coronavirus Disease Outbreak and Molecular Genetic Characteristics of Severe Acute Respiratory Syndrome-Coronavirus-2 | 0.02 | 085-213-542-828-519 | Journal of Bacteriology and Virology | 2020-03-27 | 0.2 | ||
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Covid-19 infection and mortality - A physiologist's perspective enlightening clinical features and plausible interventional strategies Zaid A. Abassi, Karl Skorecki, Samuel Noam Heyman, et al. DOI: 10.1152/ajplung.00097.2020 |
Visibilidad | Covid-19 infection and mortality - A physiologist's perspective enlightening clinical features and plausible interventional strategies | 0.02 | 025-219-286-045-101 | American Journal of Physiology-Lung Cellular and Molecular Physiology | 2020-03-27 | 0.2 | |
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A unifying structural and functional model of the coronavirus replication organelle: tracking down RNA synthesis Eric J. Snijder, Ronald W.A.L. Limpens, Adriaan H. de Wilde, et al. DOI: 10.1101/2020.03.24.005298 |
Visibilidad | A unifying structural and functional model of the coronavirus replication organelle: tracking down RNA synthesis | 0.02 | 033-515-491-193-150 | 2020-03-28 | 0.2 | ||
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Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome Taylor Kain, Patrick J. Lindsay, Neill K.J. Adhikari, et al. DOI: 10.3201/eid2606.200037 |
Visibilidad | Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome | 0.02 | 043-488-357-579-636 | Emerging Infectious Diseases | 2020-03-28 | 0.2 | |
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Antibodies in Infants Born to Mothers With COVID-19 Pneumonia Hui Zeng, Chen Xu, Junli Fan, et al. DOI: 10.1001/jama.2020.4861 |
Visibilidad | Antibodies in Infants Born to Mothers With COVID-19 Pneumonia | 0.02 | 056-805-054-199-925 | JAMA | 2020-03-28 | 0.2 | |
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Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn Lan Dong, Jinhua Tian, Songming He, et al. DOI: 10.1001/jama.2020.4621 |
Visibilidad | Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn | 0.02 | 186-763-128-363-275 | JAMA | 2020-03-28 | 0.2 | |
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SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen-Chun Liu, et al. DOI: 10.1101/2020.03.24.004655 |
Visibilidad | SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems | 0.02 | 071-224-276-037-33X | 2020-03-29 | 0.2 | ||
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Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019. Jianbo Lai, Simeng Ma, Ying Wang, et al. John Wong, Yee Sin Leo, C. C. Tan On December 31, 2019, China informed the World Health Organization of a novel viral pneumonia in the city of Wuhan, in Hubei Province. Singapore is an independent city-state 3400 km (2125 miles) from Wuhan, but as a major air hub had an average of 330 000 visitor arrivals from China each month in 2019. On January 2, 2020, Singapore’s Ministry of Health alerted all physicians to identify any patien... DOI: 10.1001/jama.2020.2467 |
Visibilidad | COVID-19 in Singapore—Current Experience: Critical Global Issues That Require Attention and Action | 0.02 | 065-585-281-661-352 | JAMA | 2020-02-21 | 0.2 | |
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MERS: Emergence of a novel human coronavirus V. Stalin Raj, Albert D. M. E. Osterhaus, Ron A. M. Fouchier, et al. A novel coronavirus (CoV) that causes a severe lower respiratory tract infection in humans, emerged in the Middle East region in 2012. This virus, named Middle East respiratory syndrome (MERS)-CoV, is phylogenetically related to bat CoVs, but other animal species like dromedary camels may potentially act as intermediate hosts by spreading the virus to humans. Although human to human transmission h... DOI: 10.1016/j.coviro.2014.01.010 |
Visibilidad | MERS: Emergence of a novel human coronavirus | 0.02 | 051-316-662-226-422 | Current Opinion in Virology | 2018-05-12 | 0.2 | |
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Update: Severe respiratory illness associated with Middle East Respiratory Syndrome Coronavirus (MERS-CoV)--worldwide, 2012-2013. None None CDC continues to work in consultation with the World Health Organization (WHO) and other partners to better understand the public health risk posed by the Middle East Respiratory Syndrome Coronavirus (MERS-CoV), formerly known as novel coronavirus, which was first reported to cause human infection in September 2012. The continued reporting of new cases indicates that there is an ongoing risk for t... |
Visibilidad | Update: Severe respiratory illness associated with Middle East Respiratory Syndrome Coronavirus (MERS-CoV)--worldwide, 2012-2013. | 0.02 | 180-002-157-973-65X | MMWR. Morbidity and mortality weekly report | 2018-05-12 | 0.2 | |
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Discovery of a Novel Coronavirus, China Rattus Coronavirus HKU24, from Norway Rats Supports the Murine Origin of Betacoronavirus 1 and Has Implications for the Ancestor of Betacoronavirus Lineage A Susanna K. P. Lau, Patrick C. Y. Woo, Kenneth S. M. Li, et al. We discovered a novel Betacoronavirus lineage A coronavirus, China Rattus coronavirus (ChRCoV) HKU24, from Norway rats in China. ChRCoV HKU24 occupied a deep branch at the root of members of Betacoronavirus 1, being distinct from murine coronavirus and human coronavirus HKU1. Its unique putative cleavage sites between nonstructural proteins 1 and 2 and in the spike (S) protein and low sequence ide... DOI: 10.1128/jvi.02420-14 |
Visibilidad | Discovery of a Novel Coronavirus, China Rattus Coronavirus HKU24, from Norway Rats Supports the Murine Origin of Betacoronavirus 1 and Has Implications for the Ancestor of Betacoronavirus Lineage A | 0.02 | 006-283-454-867-356 | Journal of Virology | 2018-05-12 | 0.2 | |
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Disease-specific B cell epitopes for serum antibodies from patients with severe acute respiratory syndrome (SARS) and serologic detection of SARS antibodies by epitope-based peptide antigens I-Ju Liu, Po-Ren Hsueh, Chin-Tarng Lin, et al. Severe acute respiratory syndrome (SARS) has emerged as a highly contagious, sometimes fatal disease. To find disease-specific B cell epitopes, phage-displayed random peptide libraries were panned on serum immunoglobulin (Ig) G antibodies from patients with SARS. Forty-nine immunopositive phage clones that bound specifically to serum from patients with SARS were selected. These phageborne peptides... DOI: 10.1086/422753 |
Visibilidad | Disease-specific B cell epitopes for serum antibodies from patients with severe acute respiratory syndrome (SARS) and serologic detection of SARS antibodies by epitope-based peptide antigens | 0.02 | 082-469-428-246-89X | The Journal of Infectious Diseases | 2018-05-12 | 0.2 | |
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SARS-Associated Viral Hepatitis Caused by a Novel Coronavirus: Report of Three Cases Tai-Nin Chau, Kam-cheong Lee, Hung Yao, et al. Liver impairment is commonly reported in up to 60% of patients who suffer from severe acute respiratory syndrome (SARS). Here we report the clinical course and liver pathology in three SARS patients with liver impairment. Three patients who fulfilled the World Health Organization case definition of probable SARS and developed marked elevation of alanine aminotransferase were included. Percutaneous... DOI: 10.1002/hep.20111 |
Visibilidad | SARS-Associated Viral Hepatitis Caused by a Novel Coronavirus: Report of Three Cases | 0.02 | 068-992-998-074-398 | Hepatology | 2018-05-12 | 0.2 | |
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Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice Marta L. DeDiego, Lecia Pewe, Enrique Alvarez, et al. Abstract Recombinant severe acute respiratory virus (SARS-CoV) variants lacking the group specific genes 6, 7a, 7b, 8a, 8b and 9b (rSARS-CoV-Δ[6–9b]), the structural gene E (rSARS-CoV-ΔE), and a combination of both sets of genes (rSARS-CoV-Δ[E,6–9b]) have been generated. All these viruses were rescued in monkey (Vero E6) cells and were also infectious for human (Huh-7, Huh7.5.1 and CaCo-2) cell li... DOI: 10.1016/j.virol.2008.03.005 |
Visibilidad | Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice | 0.02 | 007-009-570-057-320 | Virology | 2018-05-11 | 0.2 | |
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Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors Yu Yang, Zeyu Xiong, Sheng Zhang, et al. One of the hallmark findings in patients suffering from SARS (severe acute respiratory syndrome) is lymphopenia, which is the result of massive lymphocyte death. SARS-CoV (SARS coronavirus), a novel coronavirus that has been etiologically associated with SARS cases, is homologous with MHV (murine hepatitis coronavirus), and MHV small envelope E protein is capable of inducing apoptosis. We hypothes... DOI: 10.1042/bj20050698 |
Visibilidad | Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors | 0.02 | 021-773-586-396-168 | Biochemical Journal | 2018-05-12 | 0.2 | |
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The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6 Shu-Chiun Sung, Che-Yi Chao, King-Song Jeng, et al. The 8ab protein of SARS-CoV is a group-specific accessory protein, which is lost when the virus was transmitted from animals to humans due to a 29-nucleotide deletion in the ORF8ab region. Here we found that 8ab protein is associated with ER membrane at luminal surface. 8ab protein was found to up-regulate the synthesis of endogenous ER-resident chaperons involved in protein folding through the ac... DOI: 10.1016/j.virol.2009.02.021 |
Visibilidad | The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6 | 0.02 | 047-829-707-842-907 | Virology | 2018-05-11 | 0.2 | |
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Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: importance for designing SARS vaccines. Yuxian He, Qingyu Zhu, Shuwen Liu, et al. Abstract The spike (S) protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is not only responsible for receptor binding, but also a major antigenic determinant capable of inducing protective immunity. In this study, we demonstrated that the receptor-binding domain (RBD) of S protein is an important immunogenic site in patients with SARS and rabbits immunized with inactiv... DOI: 10.1016/j.virol.2005.01.034 |
Visibilidad | Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: importance for designing SARS vaccines. | 0.02 | 000-625-199-109-353 | Virology | 2018-05-12 | 0.2 | |
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Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – possible lessons from a systematic review of SARS-CoV therapy Hisham Momattin, Khurram Mohammed, Alimuddin Zumla, et al. The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory illness as well as nosocomial transmission in healthcare settings. Current international recommendations do not support... DOI: 10.1016/j.ijid.2013.07.002 |
Visibilidad | Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – possible lessons from a systematic review of SARS-CoV therapy | 0.02 | 002-808-749-577-966 | International Journal of Infectious Diseases | 2018-05-12 | 0.2 | |
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Transmission Dynamics of 2019 Novel Coronavirus (2019-nCoV) Tao Liu, Jianxiong Hu, Min Kang, et al. Background: Since December 29, 2019, pneumonia infection with 2019-nCoV has rapidly spread out from Wuhan, Hubei Province, China to most others provinces and other counties. However, the transmission dynamics of 2019-nCoV remain unclear. Methods: Data of confirmed 2019-nCoV cases before January 23, 2020 were collected from medical records, epidemiological investigations or official websites. D... DOI: 10.1101/2020.01.25.919787 [PDF] |
Visibilidad | Transmission Dynamics of 2019 Novel Coronavirus (2019-nCoV) | 0.02 | 036-749-023-257-839 | bioRxiv | 2020-02-06 | 0.2 | |
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The SARS coronavirus nucleocapsid protein induces actin reorganization and apoptosis in COS-1 cells in the absence of growth factors Milan Surjit, Boping Liu, Shahid Jameel, et al. In March 2003, a novel coronavirus was isolated from patients exhibiting atypical pneumonia, and was subsequently proven to be the causative agent of the disease now referred to as SARS (severe acute respiratory syndrome). The complete genome of the SARS-CoV (SARS coronavirus) has since been sequenced. The SARS-CoV nucleocapsid (SARS-CoV N) protein shares little homology with other members of the ... DOI: 10.1042/bj20040984 |
Visibilidad | The SARS coronavirus nucleocapsid protein induces actin reorganization and apoptosis in COS-1 cells in the absence of growth factors | 0.02 | 004-777-809-356-414 | Biochemical Journal | 2018-05-12 | 0.2 | |
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The putative protein 6 of the severe acute respiratory syndrome-associated coronavirus: expression and functional characterization. Hua Geng, Yuet Man Liu, Wai Sing Chan, et al. The SARS-CoV open reading frame 6 (ORF6) is transcribed into mRNA6 and encodes a putative 7.5 kDa accessory protein, SARS 6, with unknown function. In this study, we have confirmed the SARS 6 protein expression in lung and intestine tissues of the SARS patients and in SARS-CoV infected Vero E6 cells by immunohistochemistry. Further studies by immunoblot and confocal microscopy analyses revealed th... DOI: 10.1016/j.febslet.2005.11.007 |
Visibilidad | The putative protein 6 of the severe acute respiratory syndrome-associated coronavirus: expression and functional characterization. | 0.02 | 005-719-833-251-787 | FEBS Letters | 2018-05-12 | 0.2 | |
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Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome Albrecht von Brunn, Carola Teepe, Jeremy C. Simpson, et al. The severe acute respiratory syndrome coronavirus (SARS-CoV) genome is predicted to encode 14 functional open reading frames, leading to the expression of up to 30 structural and non-structural protein products. The functions of a large number of viral ORFs are poorly understood or unknown. In order to gain more insight into functions and modes of action and interaction of the different proteins, ... DOI: 10.1371/journal.pone.0000459 |
Visibilidad | Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome | 0.02 | 047-101-302-179-738 | PLOS ONE | 2018-05-12 | 0.2 | |
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A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines Lanying Du, Zhihua Kou, Cuiqing Ma, et al. An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in 2012 in Saudi Arabia and has now spread to eight countries. Development of effective therapeutics and vaccines is crucial to save lives and halt the spread of MERS-CoV. Here, we show that a recombinant protein containing a 21... DOI: 10.1371/journal.pone.0081587 |
Visibilidad | A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines | 0.02 | 003-376-346-248-551 | PLOS ONE | 2018-05-12 | 0.2 | |
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An Animal Model of MERS Produced by Infection of Rhesus Macaques With MERS Coronavirus Yanfeng Yao, Linlin Bao, Wei Deng, et al. In 2012, a novel coronavirus (CoV) associated with severe respiratory disease, Middle East respiratory syndrome (MERS-CoV; previously known as human coronavirus–Erasmus Medical Center or hCoV-EMC), emerged in the Arabian Peninsula. To date, 114 human cases of MERS-CoV have been reported, with 54 fatalities. Animal models for MERS-CoV infection of humans are needed to elucidate MERS pathogenesis an... DOI: 10.1093/infdis/jit590 |
Visibilidad | An Animal Model of MERS Produced by Infection of Rhesus Macaques With MERS Coronavirus | 0.02 | 026-713-667-463-710 | The Journal of Infectious Diseases | 2018-05-12 | 0.2 | |
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Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection Wai K. Leung, Ka-Fai To, Paul K.S. Chan, et al. Background & Aims: Severe acute respiratory syndrome (SARS) is a recently emerged infection from a novel coronavirus (CoV). Apart from fever and respiratory complications, gastrointestinal symptoms are frequently observed in patients with SARS but the significance remains undetermined. Herein, we describe the clinical, pathologic, and virologic features of the intestinal involvement of this new vi... DOI: 10.1016/s0016-5085(03)01215-0 |
Visibilidad | Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection | 0.02 | 000-810-020-625-388 | Gastroenterology | 2018-05-12 | 0.2 | |
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Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases Tao Ai, Zhenlu Yang, Hongyan Hou, et al. Background Chest CT is used for diagnosis of 2019 novel coronavirus disease (COVID-19), as an important complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. Purpose To ... DOI: 10.1148/radiol.2020200642 |
Visibilidad | Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases | 0.02 | 037-358-764-964-256 | Radiology | 2020-03-05 | 0.2 | |
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Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel. Mahmud Mossa-Basha, Carolyn C Meltzer, Danny C Kim, et al. DOI: 10.1148/radiol.2020200988 |
Visibilidad | Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel. | 0.01 | 089-388-230-200-706 | Radiology | 2020-03-23 | 0.1 | |
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Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. Matt Arentz, Eric Yim, Lindy Klaff, et al. DOI: 10.1001/jama.2020.4326 |
Visibilidad | Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. | 0.01 | 063-682-416-161-489 | JAMA | 2020-03-23 | 0.1 | |
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Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient Sean Wei Xiang Ong, Yian Kim Tan, Po Ying Chia, et al. Coronaviruses have been implicated in nosocomial outbreaks with environmental contamination as a route of transmission. Similarly, nosocomial transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported. However, the mode of transmission and extent of environmental contamination are unknown. DOI: 10.1001/jama.2020.3227 |
Visibilidad | Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient | 0.01 | 045-593-197-891-117 | JAMA | 2020-03-05 | 0.1 | |
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The Many Faces of COVID-19: Spectrum of Imaging Manifestations Fernando Uliana Kay, Suhny Abbara DOI: 10.1148/ryct.2020200037 |
Visibilidad | The Many Faces of COVID-19: Spectrum of Imaging Manifestations | 0.01 | 114-927-618-687-527 | Radiology: Cardiothoracic Imaging | 2020-02-21 | 0.1 | |
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Novel Coronavirus: What Neuroradiologists as Citizens of the World Need to Know. A Mahajan, J A Hirsch DOI: 10.3174/ajnr.a6526 |
Visibilidad | Novel Coronavirus: What Neuroradiologists as Citizens of the World Need to Know. | 0.01 | 030-751-075-344-373 | AJNR. American journal of neuroradiology | 2020-03-23 | 0.1 | |
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Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2 Vincent J. Munster, Friederike Feldmann, Brandi N. Williamson, et al. DOI: 10.1101/2020.03.21.001628 |
Visibilidad | Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2 | 0.01 | 113-694-184-552-930 | 2020-03-23 | 0.1 | ||
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COVID-19, Australia: Epidemiology Report 5: Reporting week ending 19:00 AEDT 29 February 2020 Olivia Williams This is the fifth epidemiological report for coronavirus disease 2019 (COVID-19), reported in Australia as at 19:00 Australian Eastern Daylight Time [AEDT] 29 February 2020. It includes data on COVID-19 cases diagnosed in Australia, the international situation and a review of current evidence. DOI: 10.33321/cdi.2020.44.20 |
Visibilidad | COVID-19, Australia: Epidemiology Report 5: Reporting week ending 19:00 AEDT 29 February 2020 | 0.01 | 066-883-940-279-088 | Communicable diseases intelligence | 2020-03-05 | 0.1 | |
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Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore. Jolin Wong, Qing Yuan Goh, Zihui Tan, et al. The coronavirus disease 2019 (COVID-19) outbreak has been designated a public health emergency of international concern. To prepare for a pandemic, hospitals need a strategy to manage their space, staff, and supplies so that optimum care is provided to patients. In addition, infection prevention measures need to be implemented to reduce in-hospital transmission. In the operating room, these prepar... DOI: 10.1007/s12630-020-01620-9 |
Visibilidad | Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore. | 0.01 | 009-515-149-020-940 | Canadian journal of anaesthesia = Journal canadien d'anesthesie | 2020-03-23 | 0.1 | |
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Host resilience to emerging coronaviruses. Amanda M Jamieson Recently, two coronaviruses, severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus, have emerged to cause unusually severe respiratory disease in humans. Currently, there is a lack of effective antiviral treatment options or vaccine available. Given the severity of these outbreaks, and the possibility of additional zoonotic coronaviruses emerging in the nea... |
Visibilidad | Host resilience to emerging coronaviruses. | 0.01 | 007-647-793-640-763 | Future virology | 2020-03-27 | 0.1 | |
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VACCINES FOR COVID-19: PERSPECTIVES, PROSPECTS, AND CHALLENGES BASED ON CANDIDATE SARS, MERS, AND ANIMAL CORONAVIRUS VACCINES Linda J. Saif DOI: 10.33590/emj/200324 |
Visibilidad | VACCINES FOR COVID-19: PERSPECTIVES, PROSPECTS, AND CHALLENGES BASED ON CANDIDATE SARS, MERS, AND ANIMAL CORONAVIRUS VACCINES | 0.01 | 110-559-186-900-504 | European Medical Journal | 2020-03-27 | 0.1 | |
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Longitudinal Assessment of COVID-19 Using a Deep Learning–based Quantitative CT Pipeline: Illustration of Two Cases Yukun Cao, Zhanwei Xu, Jianjiang Feng, et al. DOI: 10.1148/ryct.2020200082 |
Visibilidad | Longitudinal Assessment of COVID-19 Using a Deep Learning–based Quantitative CT Pipeline: Illustration of Two Cases | 0.01 | 184-025-848-714-494 | Radiology: Cardiothoracic Imaging | 2020-03-27 | 0.1 | |
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Identifying Locations with Possible Undetected Imported Severe Acute Respiratory Syndrome Coronavirus 2 Cases by Using Importation Predictions Pablo Martinez De Salazar, René Niehus, Aimee Taylor, et al. DOI: 10.3201/eid2607.200250 |
Visibilidad | Identifying Locations with Possible Undetected Imported Severe Acute Respiratory Syndrome Coronavirus 2 Cases by Using Importation Predictions | 0.01 | 057-102-679-396-924 | Emerging Infectious Diseases | 2020-03-27 | 0.1 | |
| 768-0.01 | New | Visibilidad | Covid-19: local implementation of tracing and testing programmes could enable some schools to reopen | 0.01 | 197-745-255-030-043 | BMJ | 2020-03-27 | 0.1 | ||
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Dynamic models for Coronavirus Disease 2019 and data analysis Nian Shao, Min Zhong, Yue Yan, et al. DOI: 10.1002/mma.6345 |
Visibilidad | Dynamic models for Coronavirus Disease 2019 and data analysis | 0.01 | 090-428-102-616-992 | Mathematical Methods in the Applied Sciences | 2020-03-28 | 0.1 | |
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Stay Indoors: The Slogan for Nowruz 2020 Zahid Hussain Khan, Mojghan Rahimi, Jalil Makarem DOI: 10.5812/ans.103043 |
Visibilidad | Stay Indoors: The Slogan for Nowruz 2020 | 0.01 | 007-305-885-862-101 | Archives of Neuroscience | 2020-03-28 | 0.1 | |
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SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China Jing Yu, Wen Ouyang, Melvin L. K. Chua, et al. DOI: 10.1001/jamaoncol.2020.0980 |
Visibilidad | SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China | 0.01 | 108-295-930-630-111 | JAMA Oncology | 2020-03-28 | 0.1 | |
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Coronavirus disease (COVID-19) Community Testing Team in Scotland: A 14-day review, 6 to 20 February 2020 Kate Mark, Katie Steel, Janet Stevenson, et al. DOI: 10.2807/1560-7917.es.2020.25.12.2000217 |
Visibilidad | Coronavirus disease (COVID-19) Community Testing Team in Scotland: A 14-day review, 6 to 20 February 2020 | 0.01 | 124-523-815-971-780 | Eurosurveillance | 2020-03-28 | 0.1 | |
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An Infodemiological Study on Coronavirus (COVID-19) in South Korea: Conversations and Medical News Frames on Twitter (Preprint) Han Woo Park, Sejung Park, Miyoung Chong At the end of February 2020, the virus spread rapidly in South Korea, following its initial outbreak in China, making Korea the new center of global attention. The role of social media amid the current Coronavirus pandemic have often been criticized, little systematic research has yet been conducted on this issue. Socia...
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Visibilidad | An Infodemiological Study on Coronavirus (COVID-19) in South Korea: Conversations and Medical News Frames on Twitter (Preprint) | 0.01 | 124-537-402-006-242 | 2020-03-28 | 0.1 | ||
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The Crystallography of SARS-CoV2 Suggests Its Deactivation Mohammad Bagher Fathi DOI: 10.5812/ircmj.102812 |
Visibilidad | The Crystallography of SARS-CoV2 Suggests Its Deactivation | 0.01 | 008-699-355-389-821 | Iranian Red Crescent Medical Journal | 2020-03-29 | 0.1 | |
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Covid-19 risks and response in South Asia Zulfiqar A Bhutta, Buddha Basnyat, Samir Saha, et al. DOI: 10.1136/bmj.m1190 |
Visibilidad | Covid-19 risks and response in South Asia | 0.01 | 176-649-993-666-72X | BMJ | 2020-03-29 | 0.1 | |
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Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020 Anne Kimball, Kelly M. Hatfield, Melissa Arons, et al. DOI: 10.15585/mmwr.mm6913e1 |
Visibilidad | Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020 | 0.01 | 061-949-590-012-38X | MMWR. Morbidity and Mortality Weekly Report | 2020-03-29 | 0.1 | |
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The value of mitigating epidemic peaks of COVID-19 for more effective public health responses Daniel Antunes Maciel Villela DOI: 10.1590/0037-8682-0135-2020 |
Visibilidad | The value of mitigating epidemic peaks of COVID-19 for more effective public health responses | 0.01 | 198-341-983-670-722 | Revista da Sociedade Brasileira de Medicina Tropical | 2020-03-30 | 0.1 | |
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The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. Yan-Rong Guo, Qing-Dong Cao, Zhong-Si Hong, et al. An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health emergency of international concern. The emergence of SARS-CoV-2, since the sever... DOI: 10.1186/s40779-020-00240-0 |
Visibilidad | The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. | 0.01 | 018-684-021-973-690 | Military Medical Research | 2020-03-23 | 0.1 | |
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The Struggle Against MERS-CoV (The Novel Coronavirus) Abdullah Balkhair, Khuloud Al Maamari, Fatma Ba Alawi The emergence of novel viruses is arguably viewed as a potential threat to human health. The past decade has seen the emergence of SARS-coronavirus, H5N1 (bird flu) and the H1N1 which caused a global pandemic. Furthermore, the last few months have witnessed the emergence of two novel respiratory viruses: the Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) in June 2012 in Saudi Arabia and t... DOI: 10.5001/omj.2013.66 |
Visibilidad | The Struggle Against MERS-CoV (The Novel Coronavirus) | 0.01 | 023-796-174-547-198 | Oman Medical Journal | 2018-05-12 | 0.1 | |
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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) Tao Guo, Yongzhen Fan, Ming Chen, et al. DOI: 10.1001/jamacardio.2020.1017 |
Visibilidad | Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) | 0.01 | 066-394-035-208-821 | JAMA Cardiology | 2020-03-29 | 0.1 | |
| 79-0.01 | New |
Chest CT Findings in Cases from the Cruise Ship “Diamond Princess” with Coronavirus Disease 2019 (COVID-19) Shohei Inui, Akira Fujikawa, Motoyuki Jitsu, et al. DOI: 10.1148/ryct.2020200110 |
Visibilidad | Chest CT Findings in Cases from the Cruise Ship “Diamond Princess” with Coronavirus Disease 2019 (COVID-19) | 0.01 | 154-685-517-116-380 | Radiology: Cardiothoracic Imaging | 2020-03-23 | 0.1 | |
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Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data Natalie M. Linton, Tetsuro Kobayashi, Yichi Yang, et al. The geographic spread of 2019 novel coronavirus (COVID-19) infections from the epicenter of Wuhan, China, has provided an opportunity to study the natural history of the recently emerged virus. Using publicly available event-date data from the ongoing epidemic, the present study investigated the incubation period and other time intervals that govern the epidemiological dynamics of COVID-19 infecti... DOI: 10.3390/jcm9020538 |
Visibilidad | Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data | 0.01 | 048-116-587-520-60X | Journal of Clinical Medicine | 2020-02-25 | 0.1 | |
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Positive RT-PCR Test Results in Patients Recovered From COVID-19 Lan Lan, Dan Xu, Guangming Ye, et al. Previous studies on coronavirus disease 2019 (COVID-19) mainly focused on epidemiological, clinical, and radiological features of patients with confirmed infection. Little attention has been paid to the follow-up of recovered patients. DOI: 10.1001/jama.2020.2783 |
Visibilidad | Positive RT-PCR Test Results in Patients Recovered From COVID-19 | 0.01 | 002-190-391-864-052 | JAMA | 2020-03-05 | 0.1 | |
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Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors. Yu Yang, Zeyu Xiong, Sheng Zhang, et al. One of the hallmark findings in patients suffering from SARS (severe acute respiratory syndrome) is lymphopenia, which is the result of massive lymphocyte death. SARS-CoV (SARS coronavirus), a novel coronavirus that has been etiologically associated with SARS cases, is homologous with MHV (murine hepatitis coronavirus), and MHV small envelope E protein is capable of inducing apoptosis. We hypothes... |
Visibilidad | Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors. | 0.01 | 078-770-953-062-237 | The Biochemical journal | 2018-05-12 | 0.1 | |
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Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 Jianbo Lai, Simeng Ma, Ying Wang, et al. DOI: 10.1001/jamanetworkopen.2020.3976 |
Visibilidad | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 | 0.01 | 165-155-344-724-345 | JAMA Network Open | 2020-03-27 | 0.1 | |
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2019 Novel Coronavirus—Important Information for Clinicians Carlos del Rio, Preeti N. Malani In early December 2019 a patient was diagnosed with an unusual pneumonia in the city of Wuhan, China. By December 31 the World Health Organization (WHO) regional office in Beijing had received notification of a cluster of patients with pneumonia of unknown cause from the same city. Wuhan, the capital city of Hubei Province in central China, is the nation’s seventh largest city, with a population o... DOI: 10.1001/jama.2020.1490 |
Visibilidad | 2019 Novel Coronavirus—Important Information for Clinicians | 0.01 | 072-512-225-065-755 | JAMA | 2020-02-06 | 0.1 | |
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Identification of a Severe Acute Respiratory Syndrome Coronavirus-Like Virus in a Leaf-Nosed Bat in Nigeria Phenix-Lan Quan, Cadhla Firth, Craig Street, et al. ABSTRACT Bats are reservoirs for emerging zoonotic viruses that can have a profound impact on human and animal health, including lyssaviruses, filoviruses, paramyxoviruses, and severe acute respiratory syndrome coronaviruses (SARS-CoVs). In the course of a project focused on pathogen discovery in contexts where human-bat contact might facilitate more efficient interspecies transmission of viruses,... DOI: 10.1128/mbio.00208-10 |
Visibilidad | Identification of a Severe Acute Respiratory Syndrome Coronavirus-Like Virus in a Leaf-Nosed Bat in Nigeria | 0.01 | 036-777-631-727-521 | Mbio | 2018-05-12 | 0.1 | |
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MERS coronavirus: Diagnostics, epidemiology and transmission Ian M. Mackay, Katherine E. Arden The first known cases of Middle East respiratory syndrome (MERS), associated with infection by a novel coronavirus (CoV), occurred in 2012 in Jordan but were reported retrospectively. The case first to be publicly reported was from Jeddah, in the Kingdom of Saudi Arabia (KSA). Since then, MERS-CoV sequences have been found in a bat and in many dromedary camels (DC). MERS-CoV is enzootic in DC acro... DOI: 10.1186/s12985-015-0439-5 |
Visibilidad | MERS coronavirus: Diagnostics, epidemiology and transmission | 0.01 | 043-583-211-795-307 | Virology Journal | 2018-05-12 | 0.1 | |
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Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection: Inference Using Exported Cases Sung-mok Jung, Andrei R. Akhmetzhanov, Katsuma Hayashi, et al. The exported cases of 2019 novel coronavirus (COVID-19) infection that were confirmed outside China provide an opportunity to estimate the cumulative incidence and confirmed case fatality risk (cCFR) in mainland China. Knowledge of the cCFR is critical to characterize the severity and understand the pandemic potential of COVID-19 in the early stage of the epidemic. Using the exponential growth rat... DOI: 10.3390/jcm9020523 |
Visibilidad | Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection: Inference Using Exported Cases | 0.01 | 039-791-136-029-865 | Journal of Clinical Medicine | 2020-02-21 | 0.1 | |
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Structural and functional characterization of MERS coronavirus papain-like protease Min-Han Lin, Shang-Ju Chuang, Chiao-Che Chen, et al. A new highly pathogenic human coronavirus (CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), has emerged in Jeddah and Saudi Arabia and quickly spread to some European countries since September 2012. Until 15 May 2014, it has infected at least 572 people with a fatality rate of about 30% globally. Studies to understand the virus and to develop antiviral drugs or therapy are necessary ... DOI: 10.1186/1423-0127-21-54 |
Visibilidad | Structural and functional characterization of MERS coronavirus papain-like protease | 0.01 | 032-271-531-937-886 | Journal of Biomedical Science | 2018-05-12 | 0.1 | |
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Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Xiaobo Yang, Yuan Yu, Jiqian Xu, et al. Summary Background An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in December, 2019, in Wuhan, China. Information about critically ill patients with SARS-CoV-2 infection is scarce. We aimed to describe the clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia. Methods In this single-centered, retrospectiv... DOI: 10.1016/s2213-2600(20)30079-5 |
Visibilidad | Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study | 0.01 | 021-665-106-859-672 | The Lancet Respiratory Medicine | 2020-02-25 | 0.1 | |
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Detection of Middle East respiratory syndrome coronavirus using reverse transcription loop-mediated isothermal amplification (RT-LAMP) Kazuya Shirato, Takuya Yano, Syouhei Senba, et al. Background The first documented case of Middle East Respiratory Syndrome coronavirus (MERS-CoV) occurred in 2012, and outbreaks have continued ever since, mainly in Saudi Arabia. MERS-CoV is primarily diagnosed using a real-time RT-PCR assay, with at least two different genomic targets required for a positive diagnosis according to the case definition of The World Health Organization (WHO) as of ... DOI: 10.1186/1743-422x-11-139 |
Visibilidad | Detection of Middle East respiratory syndrome coronavirus using reverse transcription loop-mediated isothermal amplification (RT-LAMP) | 0.01 | 127-810-380-205-366 | Virology Journal | 2018-05-12 | 0.1 | |
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Presumed Asymptomatic Carrier Transmission of COVID-19 Yan Bai, Lingsheng Yao, Tao Wei, et al. A novel coronavirus has resulted in an ongoing outbreak of viral pneumonia in China. Person-to-person transmission has been demonstrated, but, to our knowledge, transmission of the novel coronavirus that causes coronavirus disease 2019 (COVID-19) from an asymptomatic carrier with normal chest computed tomography (CT) findings has not been reported. DOI: 10.1001/jama.2020.2565 |
Visibilidad | Presumed Asymptomatic Carrier Transmission of COVID-19 | 0.01 | 075-845-954-789-918 | JAMA | 2020-02-25 | 0.1 | |
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The spike protein of SARS-CoV — a target for vaccine and therapeutic development Lanying Du, Yuxian He, Yusen Zhou, et al. Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease caused by a novel coronavirus, SARS-coronavirus (SARS-CoV). The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes.... DOI: 10.1038/nrmicro2090 |
Visibilidad | The spike protein of SARS-CoV — a target for vaccine and therapeutic development | 0.01 | 001-172-069-168-870 | Nature Reviews Microbiology | 2018-05-11 | 0.1 | |
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Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein. Christopher A. Nelson, Andrew Pekosz, Chung A. Lee, et al. Summary The open reading frame (ORF) 7a of the SARS-associated coronavirus (SARS-CoV) encodes a unique type I transmembrane protein of unknown function. We have determined the 1.8 A resolution crystal structure of the N-terminal ectodomain of orf7a, revealing a compact seven-stranded β sandwich unexpectedly similar in fold and topology to members of the Ig superfamily. We also demonstrate that, in... DOI: 10.1016/j.str.2004.10.010 |
Visibilidad | Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein. | 0.01 | 091-053-247-617-214 | Structure | 2018-05-12 | 0.1 | |
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In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection Isabella Eckerle, Marcel A. Müller, Stephan Kallies, et al. Background The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes symptoms similar to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), yet involving an additional component of acute renal failure (ARF) according to several published case reports. Impairment of the kidney is not typically seen in Coronavirus infections. The role of kidney infection in MERS is not understood. DOI: 10.1186/1743-422x-10-359 |
Visibilidad | In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection | 0.01 | 106-000-051-538-753 | Virology Journal | 2018-05-12 | 0.1 | |
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SARS coronavirus: a new challenge for prevention and therapy Kathryn V. Holmes A new and deadly clinical syndrome now called severe acute respiratory syndrome (SARS) was brought to the attention of the WHO by Dr. Carlo Urbani and his colleagues in a Vietnamese hospital in February 2003 (1). The WHO, the medical staffs in hospitals where the disease had appeared, and local and regional governments, together with a dozen cooperating laboratories across the globe, immediately r... DOI: 10.1172/jci18819 |
Visibilidad | SARS coronavirus: a new challenge for prevention and therapy | 0.01 | 094-836-429-541-118 | Journal of Clinical Investigation | 2018-05-11 | 0.1 | |
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The spike-protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2 and is targeted by neutralizing antibodies Stefanie Gierer, Stephanie Bertram, Franziska Kaup, et al. The novel human coronavirus EMC (hCoV-EMC), which recently emerged in Saudi Arabia, is highly pathogenic and could pose a significant threat to public health. The elucidation of hCoV-EMC interactions with host cells is critical to our understanding of the pathogenesis of this virus and to the identification of targets for antiviral intervention. Here we investigated the viral and cellular determin... DOI: 10.1128/jvi.00128-13 |
Visibilidad | The spike-protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2 and is targeted by neutralizing antibodies | 0.01 | 025-246-608-570-632 | Journal of Virology | 2018-05-12 | 0.1 | |
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Evaluation of Reverse Transcription-PCR Assays for Rapid Diagnosis of Severe Acute Respiratory Syndrome Associated with a Novel Coronavirus Wing-Cheong Yam, K. H. Chan, Leo L. M. Poon, et al. The reverse transcription (RT)-PCR protocols of two World Health Organization (WHO) severe acute respiratory syndrome (SARS) network laboratories (WHO SARS network laboratories at The University of Hong Kong [WHO-HKU] and at the Bernhard-Nocht Institute in Hamburg, Germany [WHO-Hamburg]) were evaluated for rapid diagnosis of a novel coronavirus (CoV) associated with SARS in Hong Kong. A total of 3... DOI: 10.1128/jcm.41.10.4521-4524.2003 |
Visibilidad | Evaluation of Reverse Transcription-PCR Assays for Rapid Diagnosis of Severe Acute Respiratory Syndrome Associated with a Novel Coronavirus | 0.01 | 011-308-829-798-625 | Journal of Clinical Microbiology | 2018-05-12 | 0.1 | |
| 98-0.01 | Old |
Replication of SARS coronavirus administered into the respiratory tract of African Green, rhesus and cynomolgus monkeys Josephine M. McAuliffe, Leatrice Vogel, Anjeanette Roberts, et al. SARS coronavirus (SARS-CoV) administered intranasally and intratracheally to rhesus, cynomolgus and African Green monkeys (AGM) replicated in the respiratory tract but did not induce illness. The titer of serum neutralizing antibodies correlated with the level of virus replication in the respiratory tract (AGM>cynomolgus>rhesus). Moderate to high titers of SARS-CoV with associated interstitial pne... DOI: 10.1016/j.virol.2004.09.030 |
Visibilidad | Replication of SARS coronavirus administered into the respiratory tract of African Green, rhesus and cynomolgus monkeys | 0.01 | 020-540-127-927-325 | Virology | 2018-05-12 | 0.1 | |
| 981-0.01 | Old |
Prediction of Intrinsic Disorder in MERS- CoV/HCoV-EMC Supports a High Oral-Fecal Transmission Gerard Kian-Meng Goh, A. Keith Dunker, Vladimir N. Uversky A novel coronavirus, MERS-CoV (NCoV, HCoV-EMC/2012), originating from the Middle-East, has been discovered. Incoming data reveal that the virus is highly virulent to humans. A model that categorizes coronaviuses according to the hardness of their shells was developed before the discovery of MERS-CoV. Using protein intrinsic disorder prediction, coronaviruses were categorized into three groups that... DOI: 10.1371/currents.outbreaks.22254b58675cdebc256dbe3c5aa6498b |
Visibilidad | Prediction of Intrinsic Disorder in MERS- CoV/HCoV-EMC Supports a High Oral-Fecal Transmission | 0.01 | 029-874-974-042-998 | PLOS Currents | 2018-05-12 | 0.1 | |
| 982-0.01 | Old |
Estimation of the Transmission Risk of the 2019-nCoV and Its Implication for Public Health Interventions Biao Tang, Xia Wang, Qian Li, et al. Since the emergence of the first cases in Wuhan, China, the novel coronavirus (2019-nCoV) infection has been quickly spreading out to other provinces and neighboring countries. Estimation of the basic reproduction number by means of mathematical modeling can be helpful for determining the potential and severity of an outbreak and providing critical information for identifying the type of disease i... DOI: 10.3390/jcm9020462 |
Visibilidad | Estimation of the Transmission Risk of the 2019-nCoV and Its Implication for Public Health Interventions | 0.01 | 024-076-706-347-148 | Journal of Clinical Medicine | 2020-02-09 | 0.1 | |
| 983-0.01 | Old |
Patients with RT-PCR Confirmed COVID-19 and Normal Chest CT Wenjie Yang, Fuhua Yan DOI: 10.1148/radiol.2020200702 |
Visibilidad | Patients with RT-PCR Confirmed COVID-19 and Normal Chest CT | 0.01 | 151-555-753-218-755 | Radiology | 2020-03-07 | 0.1 | |
| 984-0.01 | Old |
Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR Yicheng Fang, Huangqi Zhang, Jicheng Xie, et al. DOI: 10.1148/radiol.2020200432 |
Visibilidad | Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR | 0.01 | 060-480-337-496-438 | Radiology | 2020-02-21 | 0.1 | |
| 985-0.01 | Old |
Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China. Susan S. Chiu, Kwok-Hung Chan, Ka Wing Chu, et al. Background. Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43). Methods. We investigated the role that HCoV-NL63, HCoV-OC43, and HCoV-229E played in children hospitalized wit... DOI: 10.1086/430301 |
Visibilidad | Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China. | 0.01 | 088-388-879-348-055 | Clinical Infectious Diseases | 2018-05-12 | 0.1 | |
| 986-0.01 | Old |
A novel coronavirus outbreak of global health concern Chen Wang, Peter Horby, Frederick G. Hayden, et al. DOI: 10.1016/s0140-6736(20)30185-9 |
Visibilidad | A novel coronavirus outbreak of global health concern | 0.01 | 011-919-504-186-623 | The Lancet | 2020-01-26 | 0.1 | |
| 987-0.01 | Old |
CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus Scott A. Jeffers, Sonia M. Tusell, Laura Gillim-Ross, et al. Angiotensin-converting enzyme 2 (ACE2) is a receptor for SARS-CoV, the novel coronavirus that causes severe acute respiratory syndrome [Li, W. Moore, M. J., Vasilieva, N., Sui, J., Wong, S. K., Berne, M. A., Somasundaran, M., Sullivan, J. L., Luzuriaga, K., Greenough, T. C., et al. (2003) Nature 426, 450–454]. We have identified a different human cellular glycoprotein that can serve as an alternat... DOI: 10.1073/pnas.0403812101 |
Visibilidad | CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus | 0.01 | 031-548-667-280-855 | Proceedings of the National Academy of Sciences of the United States of America | 2018-05-12 | 0.1 |
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| 155-0.2 | cited in | 751-0.02 | |
| 156-0.19 | cited in | 115-0.8 | |
| 156-0.19 | cited in | 136-0.28 | |
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| 157-0.19 | cited in | 148-0.23 | |
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| 157-0.19 | cited in | 191-0.1 | |
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| 157-0.19 | cited in | 35-0.07 | |
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| 158-0.18 | cited in | 148-0.23 | |
| 158-0.18 | cited in | 49-0.05 | |
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| 158-0.18 | cited in | 745-0.02 | |
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| 162-0.16 | cited in | 115-0.8 | |
| 162-0.16 | cited in | 140-0.26 | |
| 162-0.16 | cited in | 168-0.14 | |
| 162-0.16 | cited in | 74-0.02 | |
| 163-0.16 | cited in | 115-0.8 | |
| 163-0.16 | cited in | 150-0.22 | |
| 163-0.16 | cited in | 154-0.2 | |
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| 163-0.16 | cited in | 175-0.13 | |
| 163-0.16 | cited in | 192-0.1 | |
| 163-0.16 | cited in | 199-0.09 | |
| 163-0.16 | cited in | 26-0.08 | |
| 163-0.16 | cited in | 3-0.08 | |
| 163-0.16 | cited in | 41-0.06 | |
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| 163-0.16 | cited in | 747-0.02 | |
| 163-0.16 | cited in | 86-0.01 | |
| 164-0.16 | cited in | 115-0.8 | |
| 164-0.16 | cited in | 133-0.31 | |
| 164-0.16 | cited in | 136-0.28 | |
| 164-0.16 | cited in | 154-0.2 | |
| 164-0.16 | cited in | 175-0.13 | |
| 164-0.16 | cited in | 192-0.1 | |
| 164-0.16 | cited in | 26-0.08 | |
| 164-0.16 | cited in | 3-0.08 | |
| 164-0.16 | cited in | 41-0.06 | |
| 164-0.16 | cited in | 94-0.01 | |
| 164-0.16 | cited in | 96-0.01 | |
| 168-0.14 | cited in | 128-0.39 | |
| 168-0.14 | cited in | 173-0.13 | |
| 168-0.14 | cited in | 28-0.08 | |
| 168-0.14 | cited in | 74-0.02 | |
| 168-0.14 | cited in | 764-0.01 | |
| 169-0.14 | cited in | 11-1.59 | |
| 169-0.14 | cited in | 112-1.01 | |
| 169-0.14 | cited in | 114-0.81 | |
| 169-0.14 | cited in | 118-0.57 | |
| 169-0.14 | cited in | 120-0.49 | |
| 169-0.14 | cited in | 123-0.43 | |
| 169-0.14 | cited in | 139-0.27 | |
| 169-0.14 | cited in | 149-0.22 | |
| 169-0.14 | cited in | 161-0.16 | |
| 169-0.14 | cited in | 177-0.12 | |
| 169-0.14 | cited in | 194-0.09 | |
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| 169-0.14 | cited in | 711-0.03 | |
| 169-0.14 | cited in | 713-0.03 | |
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| 169-0.14 | cited in | 76-0.01 | |
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| 169-0.14 | cited in | 84-0.01 | |
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| 169-0.14 | cited in | 984-0.01 | |
| 170-0.14 | cited in | 115-0.8 | |
| 170-0.14 | cited in | 119-0.57 | |
| 170-0.14 | cited in | 158-0.18 | |
| 170-0.14 | cited in | 162-0.16 | |
| 170-0.14 | cited in | 168-0.14 | |
| 170-0.14 | cited in | 29-0.08 | |
| 170-0.14 | cited in | 74-0.02 | |
| 173-0.13 | cited in | 143-0.24 | |
| 173-0.13 | cited in | 86-0.01 | |
| 174-0.13 | cited in | 115-0.8 | |
| 174-0.13 | cited in | 134-0.29 | |
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| 174-0.13 | cited in | 150-0.22 | |
| 174-0.13 | cited in | 190-0.11 | |
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| 174-0.13 | cited in | 26-0.08 | |
| 174-0.13 | cited in | 57-0.05 | |
| 174-0.13 | cited in | 696-0.04 | |
| 174-0.13 | cited in | 738-0.02 | |
| 174-0.13 | cited in | 86-0.01 | |
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| 175-0.13 | cited in | 130-0.34 | |
| 175-0.13 | cited in | 136-0.28 | |
| 175-0.13 | cited in | 150-0.22 | |
| 175-0.13 | cited in | 179-0.12 | |
| 175-0.13 | cited in | 190-0.11 | |
| 175-0.13 | cited in | 26-0.08 | |
| 175-0.13 | cited in | 3-0.08 | |
| 175-0.13 | cited in | 6-0.05 | |
| 175-0.13 | cited in | 67-0.04 | |
| 175-0.13 | cited in | 732-0.02 | |
| 175-0.13 | cited in | 747-0.02 | |
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| 175-0.13 | cited in | 86-0.01 | |
| 175-0.13 | cited in | 986-0.01 | |
| 179-0.12 | cited in | 136-0.28 | |
| 180-0.12 | cited in | 188-0.11 | |
| 180-0.12 | cited in | 2-0.09 | |
| 180-0.12 | cited in | 32-0.07 | |
| 180-0.12 | cited in | 93-0.01 | |
| 181-0.12 | cited in | 119-0.57 | |
| 181-0.12 | cited in | 122-0.43 | |
| 181-0.12 | cited in | 128-0.39 | |
| 181-0.12 | cited in | 148-0.23 | |
| 181-0.12 | cited in | 152-0.21 | |
| 181-0.12 | cited in | 155-0.2 | |
| 181-0.12 | cited in | 157-0.19 | |
| 181-0.12 | cited in | 158-0.18 | |
| 181-0.12 | cited in | 162-0.16 | |
| 181-0.12 | cited in | 180-0.12 | |
| 181-0.12 | cited in | 187-0.11 | |
| 181-0.12 | cited in | 188-0.11 | |
| 181-0.12 | cited in | 189-0.11 | |
| 181-0.12 | cited in | 191-0.1 | |
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| 181-0.12 | cited in | 198-0.09 | |
| 181-0.12 | cited in | 2-0.09 | |
| 181-0.12 | cited in | 29-0.08 | |
| 181-0.12 | cited in | 35-0.07 | |
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| 181-0.12 | cited in | 49-0.05 | |
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| 181-0.12 | cited in | 693-0.04 | |
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| 181-0.12 | cited in | 721-0.03 | |
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| 181-0.12 | cited in | 74-0.02 | |
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| 181-0.12 | cited in | 751-0.02 | |
| 181-0.12 | cited in | 764-0.01 | |
| 181-0.12 | cited in | 82-0.01 | |
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| 181-0.12 | cited in | 92-0.01 | |
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| 181-0.12 | cited in | 987-0.01 | |
| 187-0.11 | cited in | 38-0.06 | |
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| 187-0.11 | cited in | 741-0.02 | |
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| 187-0.11 | cited in | 92-0.01 | |
| 188-0.11 | cited in | 115-0.8 | |
| 188-0.11 | cited in | 119-0.57 | |
| 188-0.11 | cited in | 152-0.21 | |
| 188-0.11 | cited in | 29-0.08 | |
| 188-0.11 | cited in | 715-0.03 | |
| 189-0.11 | cited in | 153-0.21 | |
| 189-0.11 | cited in | 197-0.09 | |
| 189-0.11 | cited in | 35-0.07 | |
| 189-0.11 | cited in | 36-0.07 | |
| 189-0.11 | cited in | 721-0.03 | |
| 190-0.11 | cited in | 115-0.8 | |
| 190-0.11 | cited in | 130-0.34 | |
| 191-0.1 | cited in | 119-0.57 | |
| 191-0.1 | cited in | 158-0.18 | |
| 191-0.1 | cited in | 162-0.16 | |
| 191-0.1 | cited in | 5-0.05 | |
| 191-0.1 | cited in | 75-0.02 | |
| 192-0.1 | cited in | 136-0.28 | |
| 192-0.1 | cited in | 150-0.22 | |
| 192-0.1 | cited in | 154-0.2 | |
| 192-0.1 | cited in | 174-0.13 | |
| 192-0.1 | cited in | 175-0.13 | |
| 192-0.1 | cited in | 26-0.08 | |
| 192-0.1 | cited in | 3-0.08 | |
| 192-0.1 | cited in | 738-0.02 | |
| 192-0.1 | cited in | 779-0.01 | |
| 192-0.1 | cited in | 86-0.01 | |
| 193-0.1 | cited in | 115-0.8 | |
| 193-0.1 | cited in | 119-0.57 | |
| 193-0.1 | cited in | 122-0.43 | |
| 193-0.1 | cited in | 128-0.39 | |
| 193-0.1 | cited in | 137-0.27 | |
| 193-0.1 | cited in | 148-0.23 | |
| 193-0.1 | cited in | 152-0.21 | |
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| 193-0.1 | cited in | 156-0.19 | |
| 193-0.1 | cited in | 158-0.18 | |
| 193-0.1 | cited in | 162-0.16 | |
| 193-0.1 | cited in | 168-0.14 | |
| 193-0.1 | cited in | 188-0.11 | |
| 193-0.1 | cited in | 25-0.08 | |
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| 193-0.1 | cited in | 29-0.08 | |
| 193-0.1 | cited in | 694-0.04 | |
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| 193-0.1 | cited in | 719-0.03 | |
| 193-0.1 | cited in | 72-0.03 | |
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| 193-0.1 | cited in | 74-0.02 | |
| 193-0.1 | cited in | 743-0.02 | |
| 197-0.09 | cited in | 115-0.8 | |
| 197-0.09 | cited in | 137-0.27 | |
| 197-0.09 | cited in | 153-0.21 | |
| 197-0.09 | cited in | 715-0.03 | |
| 197-0.09 | cited in | 721-0.03 | |
| 198-0.09 | cited in | 187-0.11 | |
| 198-0.09 | cited in | 189-0.11 | |
| 198-0.09 | cited in | 35-0.07 | |
| 198-0.09 | cited in | 697-0.04 | |
| 198-0.09 | cited in | 93-0.01 | |
| 199-0.09 | cited in | 115-0.8 | |
| 199-0.09 | cited in | 128-0.39 | |
| 199-0.09 | cited in | 150-0.22 | |
| 199-0.09 | cited in | 86-0.01 | |
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| 2-0.09 | cited in | 170-0.14 | |
| 2-0.09 | cited in | 49-0.05 | |
| 2-0.09 | cited in | 693-0.04 | |
| 2-0.09 | cited in | 743-0.02 | |
| 2-0.09 | cited in | 751-0.02 | |
| 2-0.09 | cited in | 985-0.01 | |
| 21-0.09 | cited in | 115-0.8 | |
| 21-0.09 | cited in | 119-0.57 | |
| 21-0.09 | cited in | 140-0.26 | |
| 21-0.09 | cited in | 148-0.23 | |
| 21-0.09 | cited in | 152-0.21 | |
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| 21-0.09 | cited in | 158-0.18 | |
| 21-0.09 | cited in | 162-0.16 | |
| 21-0.09 | cited in | 168-0.14 | |
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| 21-0.09 | cited in | 173-0.13 | |
| 21-0.09 | cited in | 180-0.12 | |
| 21-0.09 | cited in | 191-0.1 | |
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| 21-0.09 | cited in | 199-0.09 | |
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| 21-0.09 | cited in | 26-0.08 | |
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| 21-0.09 | cited in | 35-0.07 | |
| 21-0.09 | cited in | 52-0.05 | |
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| 21-0.09 | cited in | 721-0.03 | |
| 21-0.09 | cited in | 738-0.02 | |
| 21-0.09 | cited in | 74-0.02 | |
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| 21-0.09 | cited in | 85-0.01 | |
| 21-0.09 | cited in | 92-0.01 | |
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| 21-0.09 | cited in | 96-0.01 | |
| 22-0.09 | cited in | 157-0.19 | |
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| 22-0.09 | cited in | 35-0.07 | |
| 22-0.09 | cited in | 55-0.05 | |
| 22-0.09 | cited in | 697-0.04 | |
| 26-0.08 | cited in | 128-0.39 | |
| 26-0.08 | cited in | 41-0.06 | |
| 26-0.08 | cited in | 764-0.01 | |
| 27-0.08 | cited in | 139-0.27 | |
| 28-0.08 | cited in | 115-0.8 | |
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| 29-0.08 | cited in | 162-0.16 | |
| 29-0.08 | cited in | 738-0.02 | |
| 29-0.08 | cited in | 74-0.02 | |
| 3-0.08 | cited in | 136-0.28 | |
| 3-0.08 | cited in | 150-0.22 | |
| 3-0.08 | cited in | 86-0.01 | |
| 31-0.08 | cited in | 112-1.01 | |
| 31-0.08 | cited in | 146-0.23 | |
| 31-0.08 | cited in | 177-0.12 | |
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| 31-0.08 | cited in | 25-0.08 | |
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| 31-0.08 | cited in | 692-0.04 | |
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| 31-0.08 | cited in | 71-0.03 | |
| 31-0.08 | cited in | 714-0.03 | |
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| 31-0.08 | cited in | 778-0.01 | |
| 31-0.08 | cited in | 84-0.01 | |
| 31-0.08 | cited in | 89-0.01 | |
| 35-0.07 | cited in | 158-0.18 | |
| 35-0.07 | cited in | 36-0.07 | |
| 35-0.07 | cited in | 56-0.05 | |
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| 36-0.07 | cited in | 158-0.18 | |
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| 36-0.07 | cited in | 743-0.02 | |
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| 37-0.07 | cited in | 126-0.39 | |
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| 37-0.07 | cited in | 49-0.05 | |
| 37-0.07 | cited in | 721-0.03 | |
| 37-0.07 | cited in | 92-0.01 | |
| 37-0.07 | cited in | 986-0.01 | |
| 38-0.06 | cited in | 148-0.23 | |
| 38-0.06 | cited in | 158-0.18 | |
| 38-0.06 | cited in | 49-0.05 | |
| 38-0.06 | cited in | 56-0.05 | |
| 38-0.06 | cited in | 744-0.02 | |
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| 38-0.06 | cited in | 82-0.01 | |
| 39-0.06 | cited in | 11-1.59 | |
| 39-0.06 | cited in | 112-1.01 | |
| 39-0.06 | cited in | 114-0.81 | |
| 39-0.06 | cited in | 124-0.42 | |
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| 39-0.06 | cited in | 761-0.01 | |
| 4-0.06 | cited in | 1-1.87 | |
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| 4-0.06 | cited in | 984-0.01 | |
| 41-0.06 | cited in | 115-0.8 | |
| 41-0.06 | cited in | 143-0.24 | |
| 41-0.06 | cited in | 86-0.01 | |
| 42-0.06 | cited in | 115-0.8 | |
| 42-0.06 | cited in | 130-0.34 | |
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| 42-0.06 | cited in | 150-0.22 | |
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| 43-0.05 | cited in | 713-0.03 | |
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| 49-0.05 | cited in | 148-0.23 | |
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